Sagar Buch

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To improve susceptibility quantification, a threshold-based k-space/image domain iterative approach that uses geometric information from the susceptibility map itself as a constraint to overcome the ill-posed nature of the inverse filter is introduced. Simulations were used to study the accuracy of the method and its robustness in the presence of noise. In(More)
PURPOSE To demonstrate the mapping of structures with high susceptibility values, such as the sinuses, bones and teeth, using short echo times. METHODS Four in vivo datasets were collected with a gradient-echo sequence (TE1 = 2.5 ms, TE2 = 5 ms and TE3 = 7.5 ms). Complex division was performed to remove the phase offset term and generate the phase at TE =(More)
PURPOSE To present a fully flow-compensated multiecho gradient echo sequence that can be used for MR angiography (MRA), susceptibility weighted imaging (SWI), and quantitative susceptibility mapping (QSM) and to study the effects of flow acceleration and background field gradients on flow compensation. METHODS The quality of flow compensation was(More)
Cerebral microbleeds (CMBs) are small brain hemorrhages caused by the break down or structural abnormalities of small vessels of the brain. Owing to the paramagnetic properties of blood degradation products, CMBs can be detected in vivo using susceptibility-weighted imaging (SWI). SWI can be used not only to detect iron changes and CMBs, but also to(More)
_________________________________________ Advisor Date _________________________________________ _________________________________________ _________________________________________ _________________________________________ ii DEDICATION This dissertation is dedicated to my parents: Jianwu Liu Guizhi Xi iii ACKNOWLEDGMENTS I would like to thank three(More)
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