Safoora Gharibzadeh

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We intended to evaluate the carotid intima-media thickness (CA-IMT) as a surrogate factor for atherogenesis in epileptic patients on enzyme inducer (EI) antiepileptic drugs (AEDs) or valproate (VA). The study included 71 patients with epilepsy (37 females) aged 27.7 ± 8.1 and 71 age- and sex-matched non-epileptic subjects. Patients with history of at least(More)
OBJECTIVE Using structural equation modeling, this study is one of the first efforts aimed at assessing influential factors causing gender differences in the association between health-related quality of life (HRQoL) and metabolic syndrome. METHODS A sample of 950 adults, from Tehran Lipid and Glucose Study were recruited for this cross sectional study in(More)
Thyroid dysfunction is linked with mortality and particular diseases. Intra-individual variability of measured thyroid function parameters may bias its association with outcomes, the so called "regression dilution" bias. Single measurements of thyroid function parameters result in underestimation of real associations between outcome rates with the "usual(More)
OBJECTIVE Considering the limited data available on the natural course of euthyroidism, this study was designed to evaluate the progression in time from euthyroidism to subclinical or overt hypo- or hyperthyroidism. METHODS This study was conducted within the framework of the Tehran Thyroid Cohort Study, in which 5783 individuals aged 40.4 ± 0.2 years(More)
Traditional standardization methods have been used in medical research for a long time to standardize the effect of interest for one confounder such as age. Model-based standardization extension of these methods is used when we have more than one variable produces an effect which is the population average and has marginal causal interpretation. In this(More)
UNLABELLED Nitric oxide participates in the regulation of thyroid function. AIMS The purpose of this study was to determine whether there is an association between serum nitric oxide metabolites (NOx) and free thyroxine (free T4), anti-thyroid peroxidase (anti-TPO), and thyroid-stimulating hormone (TSH) levels. METHODS Study subjects were adults, aged(More)
BACKGROUND Thyroid hormones play an important role in lipid metabolism. Overt hypothyroidism is known to be associated with increased lipid profiles, but the effect of subclinical hypothyroidism (SCH) on lipid profile remains controversial. OBJECTIVES The aim of this study was to assess the association between thyroid disorders and serum lipid levels. (More)
PURPOSE This study aimed to test a conceptual model of associations between socio-demographic and behavioral factors and obesity in the Tehran Lipid and Glucose Study (TLGS). METHODS Data from 2747 TLGS adult participants (58.3 % female) were analyzed. Socio-demographic and behavioral factors in the conceptual model were tested for their direct and(More)
BACKGROUND Subacromial impingement syndrome (SAIS) is the most common disorder of the shoulder. The evidence for the effectiveness of treatment options is inconclusive and limited. Therefore, there is a need for more evidence in this regard, particularly for long-term outcomes. HYPOTHESIS Platelet-rich plasma (PRP) would be an effective method in treating(More)
Dyslipidemia in thyroid dysfunction is mostly attributed to thyrotropin (TSH) levels, especially in subclinical disorders, but the exact role of TSH in dyslipidemia has not been explained. A total of 3 020 subjects who remained euthyroid in 3 phases of the Tehran Thyroid study were enrolled and divided according to quartiles of TSH as: Q1 (0.32-1.02), Q2(More)