Learn More
BACKGROUND A gastroenterostomy is the most commonly performed palliative procedure in patients with gastroduodenal outflow obstruction (GOO) caused by unresectable advanced gastric and pancreatic cancer. We developed a new technique--modified Devine exclusion with vertical stomach reconstruction--and evaluated the efficacy of this procedure. METHODS We(More)
BACKGROUND/AIM The Glasgow prognostic score (GPS) is a predictor of outcome for several cancer types. The present study examined the significance of modified GPS (mGPS) in the prognosis of patients undergoing palliative surgery for stage IV gastric cancer. PATIENTS AND METHODS A total of 42 patients with stage IV gastric cancer treated with palliative(More)
Pancreatic leakage continues to occur after pancreaticoduodenectomy (PD) and it is a serious problem. It has been proposed that a normal-sized, soft, friable, and functionally normal pancreas with a thin-walled main pancreatic duct is at a greater risk of anastomotic leakage. However, despite the evaluation of various improvised procedures, pancreatic(More)
Although, a variety of techniques have been described to reduce the risk of postoperative pancreatic fistula, there is no consensus on appropriate technique for closure of the pancreatic remnant after distal pancreatectomy. We developed a new surgical technique, transduodenal pancreatic juice drainage, for preventing postoperative pancreatic fistula. The(More)
We evaluated the clinical significance of indoleamine 2,3-dioxygenase (IDO) in breast cancer. Operative specimens obtained from 30 patients with breast cancer were investigated by semiquantitative RT-PCR with specific primers against IDO. The correlations among IDO expression, clinicopathologic factors and prognosis were studied. The expression of IDO was(More)
We evaluated the clinical significance of indoleamine 2,3-dioxygenase (IDO) in esophageal squamous cell carcinomas. Operative specimens obtained from 30 patients with esophageal squamous cell carcinomas were investigated by semiquantitative RT-PCR with specific primers against IDO. The correlations among IDO expression, clinicopathologic factors and(More)
We evaluated a clinical significance of indoleamine 2,3-dioxygenase (IDO) in thyroid cancers. Operative specimens obtained from 20 patients with thyroid cancers were investigated by semi-quantitative RT-PCR with specific primers against IDO. The correlations among IDO expression, clinicopathologic factors and prognosis were studied. An expression of IDO was(More)
PURPOSE Idiopathic granulomatous mastitis (IGM) is a rare inflammatory pseudotumor. No therapeutic modality has been established because of the rareness of this disease. The aim of this study was to investigate the clinical course of IGM treated with corticosteroid, and to evaluate the optimal methods of observation during corticosteroid therapy of IGM. (More)
Vitamin D receptor (VDR), a nuclear receptor that regulates calcium homeostasis, has been found to function as a receptor for secondary bile acids. Because the in vivo role of VDR in bile acid metabolism remains unknown, we investigated the effect of VDR activation in a mouse model of cholestasis. We treated mice with 1alpha-hydroxyvitamin D(3)(More)
AIM To evaluate the role and outcome of pericardiocentesis with intrapericardial cisplatin instillation for malignant pericardial effusion resulting from esophageal cancer. METHODS We retrospectively studied 7 patients who underwent pericardiocentesis with intrapericardial cisplatin instillation for malignant pericardial effusion resulting from esophageal(More)