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Transcriptome Analysis of Mouse Brain Infected with Toxoplasma gondii
- Sachi Tanaka, M. Nishimura, Fumiaki Ihara, J. Yamagishi, Yutaka Suzuki, Y. Nishikawa
- BiologyInfection and Immunity
- 15 July 2013
Positive correlations were found between the numbers of parasites in the infected mouse brains and the expression levels of genes involved in host immune responses, and differential gene expression was observed between mice exhibiting the clinical signs of toxoplasmosis and those that did not.
Relationship of Enhanced Butyrate Production by Colonic Butyrate-Producing Bacteria to Immunomodulatory Effects in Normal Mice Fed an Insoluble Fraction of Brassica rapa L
- Sachi Tanaka, Kana Yamamoto, Kazuki Yamada, Kanon Furuya, Y. Uyeno
- Biology, MedicineApplied and Environmental Microbiology
- 26 February 2016
It is demonstrated that inclusion of the boiled-water-insoluble fraction of B. rapa L. can alter the composition of the gut microbiota to decrease the numbers of Bacteroidetes and to increase the number of butyrate-producing bacteria, either of which may be involved in the observed shift in the production of splenic IL-10.
Antioxidant and cytoprotective activities of extracts prepared from fruit and vegetable wastes and by-products.
Procyanidin B2 gallates inhibit IFN‐&ggr; and IL‐17 production in T cells by suppressing T‐bet and ROR&ggr;t expression
Toll-like receptor-dependent IL-12 production by dendritic cells is required for activation of natural killer cell-mediated Type-1 immunity induced by Chrysanthemum coronarium L.
MicroRNA 16-5p is upregulated in calorie-restricted mice and modulates inflammatory cytokines of macrophages.
Role of the chemokine receptor CCR5-dependent host defense system in Neospora caninum infections
- Chisa Abe, Sachi Tanaka, M. Nishimura, Fumiaki Ihara, X. Xuan, Y. Nishikawa
- BiologyParasites & Vectors
- 6 January 2015
Findings show that migration and activation of immune cells via CCR5 is required for controlling N. caninum parasites during the early phase of the infection.
Enhancement of natural killer activity and IFN-γ production in an IL-12-dependent manner by a Brassica rapa L.
- Kana Yamamoto, Kanon Furuya, Kazuki Yamada, F. Takahashi, Chisato Hamajima, Sachi Tanaka
- BiologyBioscience, biotechnology, and biochemistry
- 1 April 2018
Findings suggest that B. rapa L. is a potentially promising immuno-improving material, and it might be useful for preventing immunological disorders such as infections and cancers by activating innate immunity.
Characterization of Microbiota that Influence Immunomodulatory Effects of Fermented Brassica rapa L
- B. Sandagdorj, Chisato Hamajima, T. Kawahara, J. Watanabe, Sachi Tanaka
- Biology, MedicineMicrobes and environments
- 1 June 2019
The results suggest that the Lactobacillus species present in fermented B. rapa L. are beneficial for manufacturing vegetables with immunomodulatory effects.