Sachi Sri Kantha

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  • H Matsumura, T Nakajima, +6 authors O Hayaishi
  • Proceedings of the National Academy of Sciences…
  • 1994
The site of action for the sleep-promoting effect of prostaglandin (PG) D2 was extensively examined in the brain of adult male rats (n = 231). PGD2 was administered at 100 pmol/0.2 microliter per min for 6 hr (2300-0500 hr) through chronically implanted microdialysis probes or infusion cannulae. Among the administrations of PDG2 by dialysis probes (n =(More)
Seasonal changes in the in vivo levels of the prostaglandins (PGs) PGD2, PGE2, and PGF2(alpha) were measured in the brain of the male Asian chipmunk, Tamias asiaticus (n = 111), which underwent hibernation during the period between November and March. The mean level of PGD2 ranged from 36.0 to 85.2 pg/g tissue from June to October and remained essentially(More)
The life of 19th century Swedish chemist cum inventor Alfred Nobel can be conveniently divided into two equal phases: pre-nitroglycerine phase (1833-1863) and nitroglycerine phase (1864-1896). According to the records of Ragnar Sohlman, his assistant during his last year of life, Nobel's physical condition began to decline towards the end of the 1870s, and(More)
L- Carnosine (beta-alanyl L-histidine), occurring abundantly in skeletal muscles, has been suggested to possess antioxidant and anti-aging properties. Using three different experimental approaches (microscopic, flow cytometric and ELISA for one of the markers of DNA oxidative damage) this study on rat embryonic fibroblasts demonstrates that L-carnosine at(More)
The significance of the 1890 tetanus antitoxin paper by von Behring and Kitasato in the development of a new discipline, immunology, is reviewed. The possible reasons why Kitasato lost the first Nobel Prize for medicine to von Behring are presented. These are as follows: (1) The Nobel selection committee literally interpreted Alfred Nobel's will to award(More)
By his own admission, Albert Einstein, 'started to talk comparatively late ... certainly not younger than three', and also had 'poor memory of words', during his childhood years. If lesions in Brodmann Area 39 of the cerebral hemisphere results in dyslexia, the 1985 report on the study of Einstein's brain that the neuron:glial ratio of Area 39 in the left(More)
  • S S Kantha
  • Progress in food & nutrition science
  • 1990
Since the establishment of a new social order in 1949, China's attempts to feed and nurture its large population has been a topic of serious study in many disciplines. This review focuses on dietary sources of Chinese population and incidence, increase and decline of important diet related health disorders in China during the last four decades. Literature(More)
The scientific productivity of Albert Einstein was compared to that of designated controls Karl Landsteiner (an experimental scientist) and Sigmund Freud (an eminent theorist). Three assumptions made for this comparison were (1) that Einstein and his designated controls had equal scientific stature; (2) that their publications were produced in a similar, if(More)
Albert Einstein had at least six medical friends who influenced his thoughts. In each period (Munich, Switzerland, Berlin and Princeton) of his life, one could identify the medically qualified individuals with whom Einstein was in close contact. These include Max Talmey, Heinrich Zangger, George Nicolai, Hans Mühsam, Janos Plesch and Gustav Bucky. They(More)
Calreticulin (Crt) is a molecular chaperone ubiquitously present in the endoplasmic reticulum. In non-human primates, age-related occurrence of anti-Crt antibody has not been reported. We developed an ELISA assay for an anti-Crt antibody and determined the age-related increase in the levels of anti-Crt antibody in three groups of cynomolgus monkeys:(More)