Sachi N. Shah

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The molecular underpinnings of synaptic vesicle fusion for fast neurotransmitter release are still unclear. Here, we used a single vesicle-vesicle system with reconstituted SNARE and synaptotagmin-1 proteoliposomes to decipher the temporal sequence of membrane states upon Ca(2+)-injection at 250-500 μM on a 100-ms timescale. Furthermore, detailed membrane(More)
In synaptic terminals, complexin is thought to have inhibitory and activating roles for spontaneous "mini" release and evoked synchronized neurotransmitter release, respectively. We used single vesicle-vesicle microscopy imaging to study the effect of complexin-1 on the on-rate of docking between vesicles that mimic synaptic vesicles and the plasma(More)
H.264 video compression standard has already been introduced in new electronic gadgets such as mobile phones and digital video players, and has gained fast acceptance by end users. Service providers such as online video storage and telecommunications companies are also beginning to adopt H.264 standard. The key element to high performance of video(More)
Ad hoc is a Latin word which describes solutions for this or specific purpose. In the world of computer network, an ad hoc network refers to a network connection which established for a single session and does not require wireless base station; they are on-the-fly networks. Energy, security and selfishness have been amongst the most popular issues for(More)
In a network, the process of selecting the best path is called routing. Routing is necessary to establish a communication between mobile nodes. In an ad-hoc network, routing becomes more challenging due to the assumption of the traditional routing protocols about friendliness between nodes in the network. Various network layer attacks can be launched which(More)
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