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Endometriosis is a frequent gynecological disease, which is crucially dependent on the process of angiogenesis. However, the underlying regulatory mechanisms of blood vessel development are still poorly understood. CK2 is a pleiotropic protein kinase, which is implicated in the regulation of various cellular processes including angiogenesis. Herein we(More)
The expression of apolipoprotein (apo) B can be modulated by mRNA editing, a unique posttranscriptional base change in the apo B mRNA. Apo B-48, the translation product of edited apo B mRNA, is not a precursor of the atherogenic low density lipoproteins and lipoprotein(a). In humans and various other mammals, the apo B mRNA is edited in the intestine but(More)
Nitric oxide (NO) is considered to contribute to the impairment of B cell function in insulin-dependent diabetes mellitus. The effects of compounds that release NO were tested on the membrane potential and ionic currents of mouse pancreatic B cells using intracellular microelectrodes and the whole-cell patch-clamp technique. S-Nitrosocysteine led to a(More)
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