Sabine Poppenborg

Publications4
h-index2
Citations29
Highly Influential Citations1
Claim Author Page
Author pages are created from data sourced from our academic publisher partnerships and public sources.

Recommended Authors

  • J. Boos
  • 272 Publications • 7,125 Citations
  • T. Ishida
  • 248 Publications • 8,347 Citations
  • H. Kiwada
  • 235 Publications • 9,078 Citations
  • G. Hempel
  • 202 Publications • 3,744 Citations
  • Publications
  • Influence
Impact of anti-PEG IgM antibodies on the pharmacokinetics of pegylated asparaginase preparations in mice.
TLDR
Early loss of asparaginase activity as observed in serum of ALL patients is a complex process and cannot be explained solely by the existence of pre-existing anti-PEG antibodies.
Comparative pharmacokinetic/pharmacodynamic characterisation of a new pegylated recombinant E. colil-asparaginase preparation (MC0609) in Beagle dog
TLDR
The new pegylated recombinant l-asparaginase preparation MC0609 revealed striking differences in PK/PD properties compared with Oncaspar® in rat and dog.
Challenges in the analytical characterization of PEGylated asparaginase
Abstract The development of a biosimilar as defined by the European Medicines Agency and the United States Food and Drug Administration looks attractive from the financial and market perspective.…
Contributors