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Tiotropium Respimat inhaler and the risk of death in COPD.
BACKGROUND Tiotropium delivered at a dose of 5 μg with the Respimat inhaler showed efficacy similar to that of 18 μg of tiotropium delivered with the HandiHaler inhalation device inExpand
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The Respimat® Development Story: Patient-Centered Innovation
AbstractThe Respimat® Soft Mist™ Inhaler represents a unique delivery system for respiratory medications, using an innovative concept with major technological advancements made during prototypeExpand
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A Handling Study to Assess Use of the Respimat® Soft Mist™ Inhaler in Children Under 5 Years Old
Abstract Background: Respimat® Soft Mist™ Inhaler (SMI) is a hand-held device that generates an aerosol with a high, fine-particle fraction, enabling efficient lung deposition. The study objectiveExpand
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Tiotropium Respimat in cystic fibrosis: Phase 3 and Pooled phase 2/3 randomized trials.
BACKGROUND Tiotropium Respimat improved lung function in a phase 2 trial in patients with cystic fibrosis (CF). We investigated its efficacy and safety in a phase 3 trial, including a pre-specifiedExpand
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Pooled analysis of tiotropium Respimat(®) pharmacokinetics in cystic fibrosis.
Tiotropium is the first bronchodilator to be studied systematically in cystic fibrosis (CF). We investigated whether any intrinsic or extrinsic factors affected pharmacokinetic (PK) parameters ofExpand
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61 Tiotropium Respimat in cystic fibrosis: Efficacy and safety results of phase III randomized placebo-controlled trial
F. Ratjen1, P. Koker2, D. Geller3, B. Langellier-Cocteaux4, F. Le Maulf4, S. Kattenbeck5, P. Moroni-Zentgraf6, J.S. Elborn7. 1The Hospital of Sick Children, Toronto, Canada; 2Boehringer IngelheimExpand
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A Handling Study to Assess the Use of the Respimat® Soft Mist™ Inhaler in Children Aged 4–12 Years
IntroductionThe Respimat® Soft Mist™ Inhaler (SMI) is a hand-held device that generates an aerosol with a high fine-particle fraction, enabling efficient lung deposition. Inhalation therapy forExpand
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