Sabine Enzinger

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Multidrug resistance may pose a serious problem to antifungal therapy. The Candida albicans Cdr2p is one of two ATP-binding cassette (ABC) transporters mediating antifungal resistance in vivo through increased drug efflux. Echinocandins such as caspofungin represent the newest class of antifungals that target cell wall synthesis. We show here by agar plate(More)
Introduction of nonselectable mutations into the genome of embryonic stem cells by homologous recombination allows to investigate the function of genes at the molecular level and has been achieved, however, at very low efficiencies by the Hit and Run, Tag and Exchange, and Double Replacement strategies. Comparing those strategies at a single locus with(More)
The aim of this study was to investigate the antibacterial effect of larch wood using microbiological methods. The bacterial strains used for conducting the experiments were Klebsiella pneumoniae (K. pneumoniae) and methicillin-resistant Staphylococcus aureus (MRSA). Wooden cubes as well as wood shavings from larch heartwood and larch sapwood were used as(More)
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