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  • Sabine Ehrt, Dirk Schnappinger, +6 authors Cf Nathan
  • Medicine
  • The Journal of experimental medicine
  • 2001
  • Macrophage activation determines the outcome of infection by Mycobacterium tuberculosis (Mtb). Interferon-gamma (IFN-gamma) activates macrophages by driving Janus tyrosine kinase (JAK)/signalContinue Reading
  • Sheetal Gandotra, Sihyug Jang, Peter J Murray, Padmini Salgame, Sabine Ehrt
  • Biology, Medicine
  • Infection and immunity
  • 2007 (First Publication: 1 November 2007)
  • Nucleotide-binding oligomerization domain proteins (NODs) are modular cytoplasmic proteins implicated in the recognition of peptidoglycan-derived molecules. NOD2 has recently been shown to beContinue Reading
  • Joeli Marrero, Kyu Y. Rhee, Dirk Schnappinger, Kevin Pethe, Sabine Ehrt
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 2010 (First Publication: 3 May 2010)
  • Metabolic adaptation to the host niche is a defining feature of the pathogenicity of Mycobacterium tuberculosis (Mtb). In vitro, Mtb is able to grow on a variety of carbon sources, but mountingContinue Reading