Sabine Bergelt

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Monoclonal antibodies (mAbs) have been developed over the past years as promising anticancer therapeutics. The conjugation of tumor specific mAbs with cytotoxic molecules has been shown to improve their efficacy dramatically. These bifunctional immunotoxins, consisting of covalently linked antibodies and protein toxins, possess considerable potential in(More)
In response to advances in proteomics research and the use of proteins in medical and biotechnological applications, recombinant protein production and the design of specific protein characteristics and functions has become a widely used technology. In this context, protein fusion tags have been developed as indispensable tools for protein expression,(More)
Wir berichten über einen 34-jährigen Patienten, der sich aufgrund Meläna und Hämatemesis in unserer Klinik vorstellte. Die endoskopische Diagnostik zeigte einen riesigen, breitbasigen Polypen im Duodenum, der die Blutungsquelle darstellte. Der 10 cm lange Tumor wurde offen-chirurgisch transduodenal reseziert, histologisch wurde ein Hamartom des Duodenums(More)
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