Sabine Bensamoun

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PURPOSE To measure the elastic properties of the vastus lateralis (VL), vastus medialis (VM), and sartorius (Sr) muscles using magnetic resonance elastography (MRE). MATERIALS AND METHODS To obtain a normative database of the aforementioned muscles, oblique scan directions were prescribed passing through each muscle. Shear waves were induced into the(More)
Magnetic resonance elastography (MRE) is capable of noninvasively quantifying the mechanical properties of skeletal muscles in vivo. This information can be clinically useful to understand the effects of pathologies on the mechanical properties of muscle and to quantify the effects of treatment. Advances in inversion algorithms quantify muscle anisotropy in(More)
PURPOSE To measure the stiffness of the vastus medialis (VM) in hyperthyroid patients before and after treatment. MATERIALS AND METHODS A total of five healthy euthyroid patients and five hyperthyroid patients were tested using magnetic resonance elastography (MRE), which involves the induction of shear waves in the thigh muscles using a pneumatic driver(More)
OBJECTIVE To explore the feasibility of using a new magnetic resonance imaging (MRI) technique--magnetic resonance elastography (MRE)--to identify and quantitate the nature of myofascial taut bands. DESIGN This investigation consisted of 3 steps. The first involved proof of concept on gel phantoms, the second involved numeric modeling, and the third(More)
PURPOSE To demonstrate the feasibility of 1D MR elastography (MRE) to rapidly assess skeletal muscle stiffness in vivo. MATERIALS AND METHODS Shear waves were induced in the vastus medialis muscle (VM) using a pneumatic driver at 90 Hz and 2D MRE data were collected. Spatially selective excitations were used to produce 1D projections of MRE data oriented(More)
TGFbeta inducible early gene-1 (TIEG) is a member of the Sp/Krüppel-like transcription factor family originally cloned from human osteoblasts. We have previously demonstrated that TIEG plays a role in the expression of important osteoblast marker genes and in the maturation/differentiation of osteoblasts. To elucidate the function of TIEG in skeletal(More)
BACKGROUND The porosity of human cortical bone is one of the major parameters conditioning bone strength. The purpose of this study was to validate the characterization of human cortical bone microarchitecture using microcomputed tomography (microCT). To validate this microCT technique, the structural measurements were compared with other methods such as(More)
OBJECTIVE To investigate and compare the spatial distribution of velocity with that of the microstructural properties (dimension of the haversian canal, percentage of porosity) on cross section of cortical bone. DESIGN Experimental investigations permitted to quantify variation of acoustic properties related with that of the microstructural properties. (More)
We report the ability of amino- and carboxyl-modified MCM-41 mesoporous silica nanoparticles (MSN) to deliver gene in vivo in rat Achilles tendons, despite their inefficiency to transfect primary tenocytes in culture. We show that luciferase activity lasted for at least 2 weeks in tendons injected with these MSN and a plasmid DNA (pDNA) encoding the(More)
The purpose of this study is to characterize the muscle architecture of children and adults using magnetic resonance elastography and ultrasound techniques. Five children (8-12 yr) and seven adults (24-58 yr) underwent both tests on the vastus medialis muscle at relaxed and contracted (10% and 20% of MVC) states. Longitudinal ultrasonic images were(More)