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  • Pauli Antero Puolakkainen, Rolf A. Brekken, Sabeeha Muneer, E. Helene Sage
  • Biology, Medicine
  • Molecular cancer research : MCR
  • 2004 (First Publication: 1 April 2004)
  • SPARC, a matricellular glycoprotein, modulates cellular interaction with the extracellular matrix (ECM). Tumor growth and metastasis occur in the context of the ECM, the levels and deposition ofExpand
  • Shanna A. Arnold, Emilia Mira, +5 authors Rolf A. Brekken
  • Biology, Medicine
  • Experimental biology and medicine
  • 2008 (First Publication: 1 July 2008)
  • Pancreatic adenocarcinoma is characterized by desmoplasia, local invasion, and metastasis. These features are regulated in part by MMP9 and SPARC. To explore the interaction of SPARC and MMP9 inExpand