Sabarish Ayyappan

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The Ewing’s sarcoma family can present diagnostic difficulties. In the past the basis of diagnosis has been a exclusion. Identification of a specific translocation especially t(11; 22) (EWS-FLI 1 fusion gene), which is seen in nearly 85% of Ewing’s sarcoma cases can help in precise diagnosis. We have carried out a study on twenty patient samples diagnosed(More)
Esophageal and gastric cancer incidence has been increasing worldwide. Most cases are diagnosed in advanced stages, and current therapy has not been able to improve the modest survival rates after diagnosis. Epidermal growth factor receptor expression has been found to correlate with poor prognosis and aggressive disease in esophagogastric cancers.(More)
BACKGROUND AND OBJECTIVES Lung cancer presentation and decision-making in the very elderly patient population, 80 years of age and older, was studied given the projected increase in cancer incidence in the very elderly and yet only limited management guidelines. DESIGN AND SETTING A 10-year experience at the Unity Health System of Rochester, NY, was(More)
We report the synthesis of alloyed quaternary and quinary nanocrystals based on copper chalcogenides, namely, copper zinc selenide-sulfide (CZSeS), copper tin selenide-sulfide (CTSeS), and copper zinc tin selenide-sulfide (CZTSeS) nanoplatelets (NPLs) (∼20 nm wide) with tunable chemical composition. Our synthesis scheme consisted of two facile steps: i.e.,(More)
This study was conducted to assess the temporal changes in the status of food security in India. The food security was assessed in terms of its basic pillars—availability access and absorption. Findings reveal that though there has been a remarkable improvement in the status of food security in India, the presence of food insecurity on a large scale erodes(More)
BACKGROUND AND OBJECTIVES Sickle cell disease (SCD) is an inherited anemia that afflicts millions worldwide. Kidney disease is a major contributor to its morbidity and mortality. We examined contemporary and historical SCD populations to understand how renal disease behaved in hemoglobin SS (HbSS) compared with HbSC. DESIGN, SETTING, PARTICIPANTS, &(More)
A short term histological study was conducted to determine the impacts of technical grade synthetic pyrethroid insecticide, cypermethrin and carbamate pesticide, carbofuran on different phases of ovarian maturation of freshwater indigenous carp, Labeo rohita. Adult females of L. rohita were exposed to sublethal doses of carbofuran (0.06, 0.15 mg/L) and(More)
The role of viral co-infections and paraproteins in the development of hematological malignancies (HMs) in HIV remains unclear. Using our large database of HIV+ patients, we investigated whether co-infection and paraproteinemia increase the risk of HM. Data on demographics, hepatitis B (HBV) and hepatitis C virus (HCV) co-infections, paraproteinemia, HIV(More)
A primary need in conserving species and their habitats is defining distinct genetic entities that range from individuals to species to ecosystems and beyond. The development of molecular genetic markers revolutionized the field of fish genetics. Using DNA markers, genetic variation in the entire genome can be analysed and exploited. Here, we outline the(More)
Insulin pen devices have revolutionized the self-management of diabetes. Prefilled insulin pens are preferred by healthcare providers and patients because of ease-of-use, dosage flexibility, disposability, and widespread availability. However, like any mechanical device, these pens have the potential for mechanical malfunction. We are present a case in(More)