Sa Xiao

Siba K. Samal10
Peter L. Collins10
Shin-Hee Kim7
Anandan Paldurai7
10Siba K. Samal
10Peter L. Collins
7Shin-Hee Kim
7Anandan Paldurai
6Baibaswata Nayak
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The nine serotypes of avian paramyxoviruses (APMVs) are frequently isolated from domestic and wild birds worldwide. APMV-1, also called Newcastle disease virus, was shown to be attenuated in non-avian species and is being developed as a potential vector for human vaccines. In the present study, we extended this evaluation to the other eight serotypes by(More)
  • Shin-Hee Kim, Sa Xiao, Heather Shive, Peter L. Collins, Siba K. Samal
  • 2012
Avian paramyxovirus (APMV) serotypes 1-9 have been isolated from many different avian species. APMV-1 (Newcastle disease virus) is the only well-characterized serotype, because of the high morbidity, mortality, and economic loss caused by highly virulent strains. Very little is known about the pathogenesis, replication, virulence, and tropism of the other(More)
  • Sa Xiao, Baibaswata Nayak, Arthur Samuel, Anandan Paldurai, Mallikarjuna Kanabagattebasavarajappa, Teguh Y. Prajitno +3 others
  • 2012
Newcastle disease virus (NDV) can cause severe disease in chickens. Although NDV vaccines exist, there are frequent reports of outbreaks in vaccinated chickens. During 2009-2010, despite intense vaccination, NDV caused major outbreaks among commercial poultry farms in Indonesia. These outbreaks raised concern regarding the protective immunity of current(More)
  • Shin-Hee Kim, Sa Xiao, Heather Shive, Peter L. Collins, Siba K. Samal
  • 2013
To evaluate the role of the F protein cleavage site in the replication and pathogenicity of avian paramyxoviruses (APMVs), we constructed a reverse genetics system for recovery of infectious recombinant APMV-4 from cloned cDNA. The recovered recombinant APMV-4 resembled the biological virus in growth characteristics in vitro and in pathogenicity in vivo.(More)
We hypothesize that the continuum between generalist and specialist adaptations is an important general trade-off axis in the maintenance of local diversity, and we explore this idea with a simple model in which there are patch types to which species arrive as propagules and compete. Each patch type is defined by a competitive ranking of all species. A(More)
  • Shin-Hee Kim, Nanchaya Wanasen, Anandan Paldurai, Sa Xiao, Peter L. Collins, Siba K. Samal
  • 2013
Virulent strains of Newcastle disease virus (NDV) can cause devastating disease in chickens worldwide. Although the current vaccines are substantially effective, they do not completely prevent infection, virus shedding and disease. To produce genotype-matched vaccines, a full-genome reverse genetics system has been used to generate a recombinant virus in(More)
We introduce a spatially explicit model that evaluates how the trade-offs between the life strategies of two interacting plant species affect the outcome of their interaction along environmental severity gradients. In our model, we represent the landscape as a two-dimensional lattice, with environmental severity increasing from left to right. Two species(More)