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Stroke is a leading cause of death and serious, long-term disability worldwide. We report that rats receiving liraglutide show markedly attenuated infarct volumes and neurological deficit following ischemic insult. We have also investigated the effect of liraglutide on apoptosis and oxidative stress pathways after ischemic injury in diabetic and(More)
HLA-DR, HLA-DQ, and HLA-DP antigen expression was assessed by immunofluorescent flow cytometry on monocytes from 19 patients with active multiple sclerosis (MS), 19 with inactive MS, 7 patients with early active rheumatoid arthritis (RA), and 19 normal controls. Percentage positivity and median channel fluorescence (MCF) were determined after separation of(More)
Ecto-5'nucleotidase (5'NT) activity in the plasma membrane of peripheral blood monocytes from patients with multiple sclerosis (MS), rheumatoid arthritis (RA), myasthenia gravis (MG), motor neuron disease (MND), and from normal control subjects of similar age was determined by radioisotopic assay. The activity in unstimulated monocytes cultured for 24 and(More)
Ingestion of sodium fluoride (NaF, 5 mg/kg/body weight) and/or arsenic trioxide (As2O3, 0.5 mg/kg body weight) for 30 days and possible beneficial effects of calcium phosphate and vitamins C and E supplementation for the next 30 days on some parameters in kidney of adult male mice (Mus musculus) were examined. The combined treatment caused a significant(More)
The effects of oral administration of sodium fluoride (NaF) and/or arsenic trioxide (As2O3) at 5 and 0.5 mg/kg body weight doses, respectively, for 30 days were studied on the physiology and histology of brain (cerebral hemisphere) of adult mice (Mus musculus). Recovery after 30 additional days by some antidotes (vitamins C and E and calcium phosphate) was(More)
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