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BACKGROUND Undernutrition is common in patients admitted with stroke. We aimed to establish whether the timing and route of enteral tube feeding after stroke affected patients' outcomes at 6 months. METHODS The FOOD trials consist of three pragmatic multicentre randomised controlled trials, two of which included dysphagic stroke patients. In one trial,(More)
BACKGROUND The effect of carotid endarterectomy in lowering the risk of stroke ipsilateral to severe atherosclerotic carotid-artery stenosis is offset by complications during or soon after surgery. We compared surgery under general anaesthesia with that under local anaesthesia because prediction and avoidance of perioperative strokes might be easier under(More)
BACKGROUND Undernutrition is common in hospital patients with stroke, can develop or worsen in hospital, and is associated with poor outcomes. We aimed to establish whether routine oral nutritional supplements improve outcome after stroke. METHODS The FOOD trials are a family of three pragmatic, multicentre, randomised controlled trials. We measured the(More)
Sway was measured by static posturography in 74 healthy subjects. Four age groups were investigated: 20-40, 40-60, 60-70 and over 70 years with equal numbers of males and females in each group. Sway increased linearly with age but was not affected by gender at any age. All age groups were more dependent on proprioception than vision in the maintenance of(More)
OBJECTIVES To test the hypothesis that unilateral motor and sensory symptoms unexplained by identifiable disease are more common on the left side of the body than the right. METHODS Systematic review of the literature published since 1965. RESULTS 121 eligible studies, involving 1139 patients, were analysed. The pooled proportion of functional left(More)
BACKGROUND Dizziness is a common symptom affecting about 30% of people over the age of 65. OBJECTIVE To investigate the hypothesis that structural abnormalities of the brain and cervical cord are more common in dizzy than in non-dizzy subjects. METHODS A case-control study of subjects over the age of 65 with and without dizziness: 125 dizzy subjects and(More)
OBJECTIVES To evaluate the accuracy of routinely available non-invasive tests (spiral computed tomographic angiography (CTA), time of flight magnetic resonance angiography (MRA), and colour Doppler ultrasound (DUS)), individually and together, compared with intra-arterial digital subtraction angiography (DSA) in patients with symptomatic tight carotid(More)
BACKGROUND AND PURPOSE Coated coils have been in clinical use for several years without robust evidence to determine their safety/efficacy. The HydroCoil Endovascular Aneurysm Occlusion and Packing Study (HELPS) addresses this deficiency for the HydroCoil embolic system. This article reports periprocedural safety/operator-assessed angiographic results from(More)
OBJECTIVES The Oxfordshire Community Stroke Project (OCSP) classification is a simple clinical scheme for subdividing first ever acute stroke. Several small studies have shown that when an infarct is visible on CT or MRI, the classification predicts its site in about three quarters of patients. The aim was to further investigate this relation in a much(More)
Doctors managing acute stroke are expected to recognise signs of early infarction on CT before choosing thrombolytic treatment, according to recent trials and guidelines. The ability of 13 physicians and two neuroradiologists to recognise early infarct signs and decide whether patients should be randomised in a hypothetical stroke treatment trial was(More)