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BACKGROUND The association between depression and mortality in older community-dwelling populations is still unresolved. This study determined the effect of both minor and major depression on mortality and examined the role of confounding and explanatory variables on this relationship. METHODS A cohort of 3056 men and women from the Netherlands aged 55 to(More)
BACKGROUND Accurate assessment of the natural history of late-life depression requires frequent observation over time. In later life, depressive disorders fulfilling rigorous diagnostic criteria are relatively rare, while subthreshold disorders are common. The primary aim was to study the natural history of late-life depression, systematically comparing(More)
BACKGROUND Associations between physical health and depression are consistent across cultures among adults up to 65 years of age. In later life, the impact of physical health on depression is much more substantial and may depend on sociocultural factors. AIMS To examine cross-national differences in the association between physical health and depressive(More)
BACKGROUND Poor physical health has long been recognized to be one of the most important risk factors for depression in older adults. Since many aspects of physical health can be targeted for improvement in primary care, it is important to know whether physical health problems predict the onset and/or the persistence of depression. METHODS The study is(More)
BACKGROUND Little research has been done on the uniqueness of risk profiles for depression and anxiety in late life. AIMS Delineating risk factors for the decline of mental health in older persons, comparing risk profiles for developing symptoms of pure depression, pure anxiety and both anxiety and depression in a prospective design. METHOD Self-report(More)
BACKGROUND The temporal relationship between depression and adverse functional outcomes in older adults is ambiguous. In the present eight-wave prospective community-based study, the longitudinal effect of depression on functional limitations and disability (in terms of disability days and bed days) was studied, thereby taking into account the role of(More)
Depression is considered to be one of the most prevalent psychiatric disorders among older adults (Blazer, 1994). This has led to a growing number of studies in which the impact of potential risk factors on both the onset and the course of depression in older adults is evaluated. These studies aim at a better understanding of depression, which may help to(More)
BACKGROUND AND AIMS Some prospective studies show that depression is a risk factor for cognitive decline. So far, the explanation for the background of this association has remained unclear. The present study investigated 1) whether depression is etiologically linked to cognitive decline; 2) whether depression and cognitive decline may be the consequence of(More)
BACKGROUND The association between depression and mortality has become a topic of interest. Little is known about the association between the course of depression and mortality. METHODS In an initially non-depressed cohort (N = 325) and a depressed cohort (N = 327), depression was measured using the Center for Epidemiologic Studies Depression scale(More)
OBJECTIVE Better understanding of the relationship between pain and depression in older adults in the community is of particular importance considering the high prevalence of both conditions in these adults. In the present study, the longitudinal relationship between pain and depression in older adults was examined, thereby taking into account the role of(More)
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