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Prostaglandin E2 (PGE2) has been implicated in the suppression of T cell IL-2 production and proliferation during burn and sepsis. The present study evaluated the potential intracellular mechanism of suppressed T cell responses by assessing the activation of p59fyn kinase in T cells from septic rats as well as the T cells incubated with PGE2. p59fyn is(More)
Quercetin, a flavonoid, is found in many plants, including edible fruits and vegetables. It has been proposed that flavonoids may have potential as anticancer agents. To test an aspect of this hypothesis, we examined the effects of the flavonoid, quercetin, on the DNA synthesis of the human leukemia cell, HL-60. Quercetin induced a dose-dependent inhibition(More)
Plants have been one of the important sources of medicines since the beginning of human civilization. There is a growing demand in the present world for plant based medicines, health products, pharmaceuticals, food supplements, cosmetics etc. The antimicrobial activity of extracts of different plants has been recognized for many years for screening purpose.(More)
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