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A sensitive and specific colorimetric method for the determination of α,β-diaminopropionic acid and the Lathyrus sativus neurotoxin
Abstract A sensitive color reaction of o-phthalaldehyde (OPT) with α,β-diaminopropionic acid (DAP) is described. The reaction is used to determine specifically the DAP content in tissues of the ratExpand
Lessons from neurolathyrism: A disease of the past & the future of Lathyrus sativus (Khesari dal)
Neurolathyrism is past history in India since Lathyrus sativus (khesari dal) is no longer used as a staple. A consensus has evolved that khesari dal is harmless as part of a normal diet. L-ODAPExpand
Studies on the biosynthesis of β-n-oxalyl-l-α,β-diaminopropionic acid, the Lathyrus sativus neurotoxin
Abstract The biosynthesis of β-N- oxalyl- l -α,β- diaminopropionic acid (ODAP), HOOC· CO·NH·CH2·CH(NH2·COOH is of interest, since this neurotoxin has been isolated from the seeds of Lathyrus sativus,Expand
Neurotoxic Potential of Three Structural Analogs of β-N-oxalyl-α,β-Diaminopropanoic Acid (β-ODAP)
Lathyrism is a non-progressive motor neuron disease produced by consumption of the excitatory amino acid, 3-N-oxalyl-L-2,3-diaminopropanoic acid (β-ODAP). To learn more about the mechanismsExpand