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Defective thymocyte apoptosis and accelerated autoimmune diseases in TRAIL−/− mice
TRAIL, the tumor necrosis factor-related apoptosis-inducing ligand, selectively induces apoptosis of tumor cells, but not most normal cells. Its role in normal, nontransformed tissues is not clear.Expand
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Critical roles of TRAIL in hepatic cell death and hepatic inflammation.
The TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis of tumor cells but not most normal cells. Its role in hepatic cell death and hepatic diseases is not clear. In vitro studiesExpand
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Tumor suppressor p53 inhibits autoimmune inflammation and macrophage function.
The tumor suppressor p53 regulates apoptosis, cell cycle, and oncogenesis. To explore the roles of p53 in autoimmunity, we studied type 1 diabetes and innate immune responses using C57BL/6 miceExpand
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Organic light emitting diode improves diabetic cutaneous wound healing in rats.
A major complication for diabetic patients is chronic wounds due to impaired wound healing. It is well documented that visible red wavelengths can accelerate wound healing in diabetic animal modelsExpand
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Transcriptional regulation of type I diabetes by NF-kappa B.
Development of type I diabetes requires coordinated expression of myriad genes responsible for the initiation and progression of the disease. Expression of these genes are regulated by a small numberExpand
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Transcriptional Regulation of Type I Diabetes by NF-κB 1
Development of type I diabetes requires coordinated expression of myriad genes responsible for the initiation and progression of the disease. Expression of these genes are regulated by a small numberExpand
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Translational Regulation of Autoimmune Inflammation and Lymphoma Genesis by Programmed Cell Death 41
Both inflammatory diseases and cancer are associated with heightened protein translation. However, the mechanisms of translational regulation and the roles of translation factors in these diseasesExpand
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Reduced Apoptosis and Ameliorated Listeriosis in TRAIL-Null Mice1
Listeriosis is an infectious disease caused by the bacterium Listeria monocytogenes. Although it is well recognized that apoptosis plays a critical role in the pathogenesis of the disease, theExpand
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Increase of CD163 but not sialoadhesin on cultured peripheral blood monocytes is coordinated with enhanced susceptibility to porcine reproductive and respiratory syndrome virus infection.
Porcine reproductive and respiratory syndrome virus (PRRSV) has a restricted tropism mainly for porcine alveolar macrophages (PAMs), but not for peripheral blood monocytes (BMo) in vivo. PreviousExpand
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Roles of Bcl-3 in the Pathogenesis of Murine Type 1 Diabetes
OBJECTIVE It has long been recognized that autoimmunity is often associated with immunodeficiency. The mechanism underlying this paradox is not well understood. Bcl-3 (B-cell lymphoma 3) is anExpand
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