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NLRC5 Negatively Regulates the NF-κB and Type I Interferon Signaling Pathways
Stringent control of the NF-kappaB and type I interferon signaling pathways is critical to effective host immune responses, yet the molecular mechanisms that negatively regulate these pathways are… Expand
CYP1A1, GSTs and mEH polymorphisms and susceptibility to esophageal carcinoma: study of population from a high- incidence area in north China.
- L. Wang, S. Zheng, B. Liu, Jian-Xiang Zhou, Y. Li, J. Li
- World journal of gastroenterology
- 15 July 2003
AIM To characterize cytochrome P4501A1 (CYP1A1), glutathione S-transferases (GSTs) and microsomal epoxide hydrolase (mEH) polymorphisms in Chinese esophageal cancer patients. METHODS Multiplex… Expand
MicroRNA‐183 regulates Ezrin expression in lung cancer cells
Lung cancer is the leading cause of cancer death. However, the mechanism of lung cancer relapse and metastasis has been poorly elucidated. Recent researches have addressed the role of MicroRNAs… Expand
Identification and Characterization of a Novel Plant Phospholipase D That Requires Polyphosphoinositides and Submicromolar Calcium for Activity in Arabidopsis*
Phospholipase D (PLD; EC 184.108.40.206) has been proposed to be involved in a number of cellular processes including transmembrane signaling and membrane deterioration. PLD previously described from… Expand
[Clinical study on the efficacy of tranexamic acid in reducing postpartum blood lose: a randomized, comparative, multicenter trial].
OBJECTIVE To study the efficacy and safety of Transamin (tranexamic acid) in reducing postpartum blood loss. METHODS Four hundred primipara with term singleton pregnancy, vertex presentation,… Expand
Artificial Neural Networks Analysis of Surface-Enhanced Laser Desorption/Ionization Mass Spectra of Serum Protein Pattern Distinguishes Colorectal Cancer from Healthy Population
Purpose: The low specificity and sensitivity of the carcinoembryonic antigen test makes it not an ideal biomarker for the detection of colorectal cancer. We developed and evaluated a proteomic… Expand
Clinical significance of K-ras and BRAF mutations in Chinese colorectal cancer patients.
AIM To identify and assess mutations in the K-ras and BRAF genes in a cohort of Chinese patients with colorectal cancer (CRC) for their association with various clinicopathological parameters and… Expand
Ursolic acid inhibits proliferation and induces apoptosis of HT-29 colon cancer cells by inhibiting the EGFR/MAPK pathway
- Jian-zhen Shan, Yan-yan Xuan, S. Zheng, Qi Dong, S. Zhang
- Biology, Medicine
- Journal of Zhejiang University SCIENCE B
- 30 August 2009
ObjectiveTo investigate the effects of ursolic acid on the proliferation and apoptosis of human HT-29 colon cancer cells.Methods3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and… Expand
Association of human APOBEC3 cytidine deaminases with the generation of hepatitis virus B x antigen mutants and hepatocellular carcinoma
- Rongzhen Xu, X. Zhang, W. Zhang, Y. Fang, S. Zheng, Xiao-Fang Yu
- Biology, Medicine
- 1 December 2007
Human APOBEC3 (apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3) cytidine deaminases have been shown to be potent inhibitors of diverse retroviruses including Vif‐deficient human… Expand
Serum protein fingerprinting coupled with artificial neural network distinguishes glioma from healthy population or brain benign tumor.
- J. Liu, S. Zheng, Jie-kai Yu, J. Zhang, Z. Chen
- Medicine, Biology
- Journal of Zhejiang University. Science. B
To screen and evaluate protein biomarkers for the detection of gliomas (Astrocytoma grade I-IV) from healthy individuals and gliomas from brain benign tumors by using surface enhanced laser… Expand