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Intercountry prevalences and practices of betel‐quid use in south, southeast and eastern asia regions and associated oral preneoplastic disorders: An international collaborative study by asian…
Health risks stemming from betel‐quid (BQ) chewing are frequently overlooked by people. Updated epidemiological data on the increased BQ use among Asian populations using comparable data collection… Expand
Targeting autophagy potentiates chemotherapy-induced apoptosis and proliferation inhibition in hepatocarcinoma cells.
Induction of cell death and inhibition of cell growth are the main targets of cancer therapy. Here we evaluated the role of autophagy on chemoresistance of human hepatocarcinoma (HCC) cell lines,… Expand
CD133+CXCR4+ colon cancer cells exhibit metastatic potential and predict poor prognosis of patients
BackgroundColorectal cancer (CRC), which frequently metastasizes to the liver, is one of the three leading causes of cancer-related deaths worldwide. Growing evidence suggests that a subset of cells… Expand
Toll-like receptor 4 signaling promotes epithelial-mesenchymal transition in human hepatocellular carcinoma induced by lipopolysaccharide
BackgroundThe endotoxin level in the portal and peripheral veins of hepatocellular carcinoma (HCC) patients is higher and lipopolysaccharide (LPS), a cell wall constituent of gram-negative bacteria,… Expand
Inhibition of autophagy enhances anticancer effects of bevacizumab in hepatocarcinoma
- Xian-ling Guo, Ding Li, +9 authors L. Wei
- Biology, Medicine
- Journal of Molecular Medicine
- 10 October 2012
Angiogenesis inhibitors have long been considered desirable anticancer agents. However, it was found that many tumors could develop resistance to antiangiogenesis inhibitors. Antiangiogenic therapy… Expand
Effect of Anti-Obesity Drug on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Background Anti-obesity drugs are widely used to prevent the complications of obesity, however, the effects of anti-obesity drugs on cardiovascular risk factors are unclear at the present time. We… Expand
Antifibrotic effect of curcumin in TGF-β 1-induced myofibroblasts from human oral mucosa.
- S. Zhang, Zhao-jian Gong, W. Li, X. Wang, T. Ling
- Biology, Medicine
- Asian Pacific journal of cancer prevention…
- 31 January 2012
BACKGROUND Myofibroblasts play an important role in the development of oral submucous fibrosis (OSF). In the current study, we investigate the effect of curcumin on growth and apoptosis of… Expand
Autophagy contributes to the survival of CD133+ liver cancer stem cells in the hypoxic and nutrient-deprived tumor microenvironment.
Liver cancer stem cells (LCSCs) can drive and maintain hepatocellular carcinoma (HCC) growth, metastasis, and recurrence. Therefore, they are potentially responsible for the poor prognosis of HCC.… Expand
Population burden of betel quid abuse and its relation to oral premalignant disorders in South, Southeast, and East Asia: an Asian Betel-quid Consortium Study.
OBJECTIVES We investigated the population burden of betel quid abuse and its related impact on oral premalignant disorders (OPDs) in South, Southeast, and East Asia. METHODS The Asian Betel-Quid… Expand
Nutritional status deteriorates as the severity of diabetic foot ulcers increases and independently associates with prognosis
- S. Zhang, Z. Tang, Ping Fang, Hong-jie Qian, L. Xu, G. Ning
- Experimental and therapeutic medicine
- 30 October 2012
The prognosis for diabetic foot ulcers (DFUs) remains poor. Nutritional status has not been identified as one of the factors affecting the outcome of DFUs. Therefore, indicators correlated with… Expand