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Dilated Cardiomyopathy Caused by Aberrant Endoplasmic Reticulum Quality Control in Mutant KDEL Receptor Transgenic Mice
ABSTRACT Aberrant protein folding beyond the capacity of endoplasmic reticulum (ER) quality control leads to stress response in the ER. The Lys-Asp-Glu-Leu (KDEL) receptor, a retrieval receptor forExpand
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Pax6 is required for production and maintenance of progenitor cells in postnatal hippocampal neurogenesis
Neurogenesis is crucial for brain formation and continues to take place in certain regions of the postnatal brain including the subgranular zone (SGZ) of the hippocampal dentate gyrus (DG). Pax6Expand
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Reduced proliferative activity of primary POMGnT1-null myoblasts in vitro
Protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) is an enzyme that transfers N-acetylglucosamine to O-mannose of glycoproteins. Mutations of the POMGnT1 gene causeExpand
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Hepatocyte growth factor stimulates liver regeneration and elevates blood protein level in normal and partially hepatectomized rats.
The effects of recombinant human hepatocyte growth factor (HGF) on liver growth and function of normal and partially hepatectomized rats have been examined. HGF was continuously administered into theExpand
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Disruption of the midkine gene (Mdk) resulted in altered expression of a calcium binding protein in the hippocampus of infant mice and their abnormal behaviour
Midkine (MK) is a growth factor implicated in the development and repair of various tissues, especially neural tissues. However, its in vivo function has not been clarified.
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Expression of three nonallelic genes coding calmodulin exhibits similar localization on the central nervous system of adult rats
By Northern blot analysis with the digoxigenin‐labeled antisense RNA probes of the noncoding regions, the transcripts of three calmodulin (CaM) genes, CaMI, CaMII, and CaMIII, were separatelyExpand
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Effects of neonatal administration of 17β-estradiol, β-estradiol 3-benzoate, or bisphenol A on mouse and rat spermatogenesis☆
Bisphenol A (BPA) is a global environmental contaminant that has been implicated as a potential endocrine disruptor. In the present study, newborn rats and mice were injected subcutaneously with BPAExpand
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A comprehensive approach for establishment of the platform to analyze functions of KIAA proteins II: public release of inaugural version of InGaP database containing gene/protein expression profiles
The inaugural version of the InGaP database (Integrative Gene and Protein expression database; http://www.kazusa.or.jp/ingap/index.html) is a comprehensive database of gene/protein expressionExpand
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Alteration of inflammatory cytokine production in the injured central nervous system of tenascin-deficient mice.
Although tenascin-C (TN) is highly up-regulated during the proliferation of reactive astrocytes, little is known about the function of TN at injury sites in the central nervous system (CNS). Here,Expand
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β-estradiol 3-benzoate affects spermatogenesis in the adult mouse
beta-estradiol 3-benzoate (E(2)B) (10, 16, 20, 40, 80 and 160 microg/kg body weight) was administered daily to experimental groups of adult mice for the following periods; 2, 3 days, 1, 2, 4, and 8Expand
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