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Stereoselective Total Synthesis of (+/-)-Swainsonine Based on Endo Mode Cyclization.
A new stereoselective total synthesis of (+/-)-swainsonine is described, and the piperidine derivative thus prepared was converted into the title compound efficiently.
Co2(CO)8-mediated endo mode cyclization of epoxy-alcohol: synthesis of 2-ethynyl-3-hydroxy-2-methyltetrahydropyran and 2-ethynyl-3-hydroxy-3-methyltetrahydropyran derivatives.
The preferential endo mode cyclization over the exo one was observed in these experiments and the tetrahydropyran derivatives with the cobalt-complexed moiety were provided.
N-alkoxyalkyl derivatives -n, n-dialkylamine or salts thereof and agents for treating neurodegenerative diseases comprising the same.
Un derivado de N-alcoxialquil-N,N-dialquilamina representado por la siguiente formula general, o su sal: ** ver formula** en la que R 1 y R 2 son iguales o diferentes y representan al menos un grupo
N-alkoxyalkyl-n,n-dialkylamine derivatives or salts thereof, and agents for treating neurodegenerative diseases comprising the same
N-Alkoxyalkyl-N,N-dialkylamine derivatives of general formula [1] or salts thereof, which exhibit antihypoxic, nerve protecting and nerve regeneration promoting effects and are useful as remedies for