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Construction of a new multi-turn time-of-flight mass spectrometer.
A new type of multi-turn time-of-flight mass spectrometer was constructed, consisting of four cylindrical electric sectors and 28 electric quadrupole lenses, the size of the vacuum chamber being 60 xExpand
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Application of electrospray ionization ion trap/time-of-flight mass spectrometry for chemically-synthesized small RNAs.
In this study, we have demonstrated an accurate and rapid small RNA analytical method with both sequence determination and detailed modification analysis by electrospray ionization-ionExpand
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Analysis of the modification site in a small molecule-modified peptide by ion trap/time-of-flight hybrid mass spectrometry
Ion trap/time-of-flight hybrid mass spectrometers are powerful tools for the detailed structural analysis of modified peptides. We have analyzed Met-Lys-bradykinin modified with deoxycholate at theExpand
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A Space Time-of-Flight Mass Spectrometer for Exobiologically-Oriented Applications
Abstract A new type of multi-turn time-of-flight mass spectrometer was designed and constructed as a laboratory model of the ‘COSAC’ project of the ‘ROSETTA’ mission cometary study. This miniatureExpand
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Development of a Potential-Lift Ion Source.
Generally, an ion source is supplied with high voltage to accelerate ions. However, the high voltage on the ion source makes some difficulties in applying pulse voltage or introducing samples, etc.Expand
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Identification of Drugs by Ultra Fast Liquid Chromatography/Electrospray Ionization‐Quadrupole Ion Trap/Time‐of‐Flight Mass Spectrometry
Abstract Hybrid quadrupole ion trap/time‐of‐flight mass spectrometry (QIT/TOFMS) was applied for detection of ultra fast liquid chromatography (UFLC). The system performance for fast qualitativeExpand
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A Method to Determine Turn Numbers in Multi-Turn TOF MS
Although various multi-turn geometries of time-of-flight mass spectrometry (TOF MS) have been devised recently, they still suffer from a practical problem in analysis for a wide mass range. TheExpand
2 Identification of Phospholipid Molecular Species Using Neutral Loss Survey and MS 3 Analysis
To elucidate the functions of phospholipids, it is important to conduct analysis not only of their classes and sub-classes, but of their molecular species as well. At Shimadzu, we found thatExpand
Automated Detection of Metabolites from Liquid Chromatography/Mass Spectrometry/Mass Spectrometry Data Using Partial Least Squares with Ion Trap Time of Flight Mass Spectrometry
Metabolite identification is a critical step in drug discovery and development. Finding metabolites by comparing sample data with control data is both difficult and tedious, despite the variousExpand