• Publications
  • Influence
Genomic dissection of population substructure of Han Chinese and its implication in association studies.
To date, most genome-wide association studies (GWAS) and studies of fine-scale population structure have been conducted primarily on Europeans. Han Chinese, the largest ethnic group in the world,Expand
  • 275
  • 21
A genome-wide search for signals of high-altitude adaptation in Tibetans.
Genetic studies of Tibetans, an ethnic group with a long-lasting presence on the Tibetan Plateau which is known as the highest plateau in the world, may offer a unique opportunity to understand theExpand
  • 235
  • 18
  • PDF
Three-Dimensional Structure of I to
  • 175
  • 13
Charybdotoxin Binding in the IKs Pore Demonstrates Two MinK Subunits in Each Channel Complex
I(Ks) voltage-gated K(+) channels contain four pore-forming KCNQ1 subunits and MinK accessory subunits in a number that has been controversial. Here, I(Ks) channels assembled naturally by monomerExpand
  • 135
  • 9
The Y-chromosome landscape of the Philippines: extensive heterogeneity and varying genetic affinities of Negrito and non-Negrito groups
The Philippines exhibits a rich diversity of people, languages, and culture, including so-called ‘Negrito’ groups that have for long fascinated anthropologists, yet little is known about theirExpand
  • 66
  • 9
  • PDF
Identification of Functional Mutations in GATA4 in Patients with Congenital Heart Disease
Congenital heart disease (CHD) is one of the most prevalent developmental anomalies and the leading cause of noninfectious morbidity and mortality in newborns. Despite its prevalence and clinicalExpand
  • 45
  • 9
The p.Ser267Phe variant in SLC10A1 is associated with resistance to chronic hepatitis B
  • L. Peng, Q. Zhao, +21 authors Yiming Wang
  • Biology, Medicine
  • Hepatology
  • 1 April 2015
In the past 50 years there have been considerable efforts to identify the cellular receptor of hepatitis B virus (HBV). Recently, in vitro evidence from several groups has shown that theExpand
  • 55
  • 8
Analysis of genomic admixture in Uyghur and its implication in mapping strategy.
The Uyghur (UIG) population, settled in Xinjiang, China, is a population presenting a typical admixture of Eastern and Western anthropometric traits. We dissected its genomic structure at populationExpand
  • 148
  • 7
  • PDF
Aryl hydrocarbon receptor and NF-E2-related factor 2 are key regulators of human MRP4 expression.
Multidrug resistance protein 4 (MRP4; ABCC4) is an ATP binding cassette transporter that facilitates the excretion of bile salt conjugates and other conjugated steroids in hepatocytes and renalExpand
  • 79
  • 7
Human Migration through Bottlenecks from Southeast Asia into East Asia during Last Glacial Maximum Revealed by Y Chromosomes
Molecular anthropological studies of the populations in and around East Asia have resulted in the discovery that most of the Y-chromosome lineages of East Asians came from Southeast Asia. However,Expand
  • 69
  • 7
  • PDF