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Pharmacokinetic and pharmacodynamic modeling of the antiplatelet and cardiovascular effects of cilostazol in healthy humans
A pharmacokinetic‐pharmacodynamic model was used to analyze the relation between the plasma concentration of cilostazol, the inhibitory effect of the drug onplatelet aggregation, and the cardiovascular effects of theDrug on healthy humans.
Comparative study of combination therapy of Korean–/INS;Western medical treatment versus Western medical treatment only in acute ischemic stroke patients
Pharmacokinetics and bioavailability of oral cephalosporins, KR-984055 and its prodrugs, KR-999001 and KR-999002, in the rat
KR999001 and KR-999002 appear to be an efficient oral prodrug of KR-984055 that deserved further clinical evaluation in human and was readily cleaved to free KR- 984055.