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3-Nitropropionic acid (3-NPA), a potent antimycobacterial agent from endophytic fungi: is 3-NPA in some plants produced by endophytes?
3-Nitropropionic acid (3-NPA, 1) was found in extracts of several strains of endophytic fungi. 3-NPA (1) exhibited potent antimycobacterial activity with the minimum inhibition concentration of 3.3Expand
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Aspergillusol A, an alpha-glucosidase inhibitor from the marine-derived fungus Aspergillus aculeatus.
A new tyrosine-derived metabolite, aspergillusol A (4), was isolated on a gram scale, together with a methyl ester of 4-hydroxyphenylpyruvic acid oxime (5) and secalonic acid A, from theExpand
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Antimalarial dihydroisocoumarins produced by Geotrichum sp., an endophytic fungus of Crassocephalum crepidioides.
Three novel dihydroisocoumarin derivatives (1-3) with antimalarial, antituberculous, and antifungal activities have been isolated by bioassay-guided fractionation from an endophytic fungus,Expand
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Cytotoxic and antiplasmodial substances from marine-derived fungi, Nodulisporium sp. and CRI247-01.
Nodulisporacid A (1) was isolated from a marine-derived fungus Nodulisporium sp. CRIF1, while vermelhotin (5) was obtained from an unidentified fungus CRI247-01 (a member of the Order Pleosporales).Expand
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Spectrophotometric enzymatic cycling method using l-glutamate dehydrogenase and d-phenylglycine aminotransferase for determination of l-glutamate in foods
This report describes a new spectrophotometric method capable of determining low levels of L-glutamate. The assay is based on substrate cycling between L-glutamate dehydrogenase (G1DH) and the novelExpand
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Purification, Characterization, Gene Cloning and Sequence Analysis of a Phytase from Klebsiella pneumoniae subsp. pneumoniae XY-5
A phytase produced by the soil bacterium Klebsiella pneumoniae subsp. pneumoniae strain XY-5 was isolated and purified. The enzyme was a single chain protein with a molecular mass of 41.7 kDa, asExpand
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Endophytic fungi with anti-microbial, anti-cancer and anti-malarial activities isolated from Thai medicinal plants
A total of 81 Thai medicinal plant species collected from forests in four geographical regions of Thailand were examined for the presence of endophytic fungi with biological activity. Of 582 pureExpand
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Radical scavenging and antioxidant activities of isocoumarins and a phthalide from the endophytic fungus Colletotrichum sp.
Five known isocoumarins, monocerin (1), derivative 2, and fusarentin derivatives 3-5, and a new phthalide (6) were isolated from the endophytic fungus Colletotrichum sp. 2 selectively exhibitedExpand
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Creation of a zymogen
Cells produce proteases as inactive zymogens. Here, we demonstrate that this tactic can extend beyond proteases. By linking the N and C termini of ribonuclease A, we obstruct the active site with theExpand
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11-Hydroxymonocerin from the plant endophytic fungus Exserohilum rostratum.
A new analogue of monocerin, 11-hydroxymonocerin (2), along with monocerin (1) and 12-hydroxymonocerin (3) were isolated from cultures of Exserohilum rostratum, a fungal strain endophytic in StemonaExpand
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