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Genetic Diversity through the Looking Glass: Effect of Enrichment Bias.
The effect of enrichment bias on the diversity of 2,4-dichlorophenoxyacetate (2,4-D)-degrading (2,4-D(sup+)) bacteria recovered from soil was evaluated by comparing the diversity of isolates obtained… Expand
Breeding for host resistance: the key to sustainable potato production.
Phytophthora infestans (Mont.) de Bary, the causal agent of late-blight disease of potato, continues to be a major limiting factor to potato production worldwide. Field trials in 2009, inoculated… Expand
Mycotoxins in agriculture and food safety.
Mycotoxins can find their way into the human food chain in a variety of ways and have been shown to be present in many different foods and animal feed products. These mycotoxins can cause a toxic… Expand
Genome-wide rare variant analysis for thousands of phenotypes in over 70,000 exomes from two cohorts
- E. Cirulli, S. White, +10 authors N. Washington
- Biology, Medicine
- Nature Communications
- 28 January 2020
Understanding the impact of rare variants is essential to understanding human health. We analyze rare (MAF < 0.1%) variants against 4264 phenotypes in 49,960 exome-sequenced individuals from the UK… Expand
Genome-wide rare variant analysis for thousands of phenotypes in 54,000 exomes
Defining the effects that rare variants can have on human phenotypes is essential to advancing our understanding of human health and disease. Large-scale human genetic analyses have thus far focused… Expand
Resistance of Sárpo clones to the new strain of Phytophthora infestans, Blue-13.
A Diagnosis of ABC Transporters, ATP-binding proteins in ElizabethkingiaanophelisR26
Elizabethkingiaanophelisoriginates from mosquitos and is commonly found in soil, river waters, and reservoirs. Elizabethkingia, itself, is a bacterium that has recently (March 2016) sprung an… Expand
Selective constraints and pathogenicity of mitochondrial DNA variants inferred from a novel database of 196,554 unrelated individuals
Robust characterization of mitochondrial variation provides an opportunity to map regions under high constraint, and identify essential functional domains. We sequenced the mitochondrial genomes of… Expand