• Publications
  • Influence
Genomic Signature of Driver Genes Identified by Target Next-Generation Sequencing in Chinese Non-Small Cell Lung Cancer.
TLDR
The findings highlighted that NGS technology is more feasible and necessary than other molecular testing methods, and suggested that the special strategies are needed for drug development and targeted therapy for Chinese patients with NSCLC.
Identification of the key transcription factors in esophageal squamous cell carcinoma.
TLDR
BRCA1, SOX10, ARID3A, ZNF354C and NFIC might be the key TFs in carcinogenesis and development of ESCC by regulating their corresponding target-genes involved in cell cycle, DNA replication and oocyte meiosis pathways.
Comparison of Up-Front Minimally Invasive Esophagectomy versus Open Esophagectomy on Quality of Life for Esophageal Squamous Cell Cancer
TLDR
The OES-18 score of MIE group was significantly better than OE group at first, sixth and twelfth months after surgery, and the short-term quality of life in MIEgroup was better thanOE group.
Identification of dysregulated long non-coding RNAs/microRNAs/mRNAs in TNM I stage lung adenocarcinoma
TLDR
The aberrant expression profiling of long non-coding RNA (lncRNA) in TNM I stage (stage I) LUAD might lay the foundation for illumination of pathogenesis of LUAD and identification of potential therapeutic targets and novel diagnosis biomarkers for LUAD patients.
A Propensity-Matched Analysis of Outcomes of Patients with Clinical Stage I Non–Small Cell Lung Cancer Treated surgically or with stereotactic radiotherapy: A Meta-Analysis
TLDR
The surgery had obvious OS advantages in this meta-analysis, however, these conclusions would be proven by further studies incorporating comorbidity data, and outcomes from randomized control study.
Identification of Commonly Dysregulated Genes in Non-small-cell Lung Cancer by Integrated Analysis of Microarray Data and qRT-PCR Validation
TLDR
qRT-PCR results indicated that the meta-analysis approach in this study was acceptable, and suggested that some of the DEGs, including MMP12, COL11A1, THBS2, FAP, and CAV1, may participate in the pathology of NSCLC and could be applied as potential markers or therapeutic targets forNSCLC.
Soluble c-Met Is a Reliable and Sensitive Marker to Detect c-Met Expression Level in Lung Cancer
TLDR
Results demonstrated that plasma s-Met is a sensitive and reliable marker to detect c-Met overexpression in lung cancers, and it is independent of tumor volume.
Identification of dysregulated long non-coding RNAs/microRNAs/mRNAs in TNM I stage lung adenocarcinoma.
TLDR
The aberrant expression profiling of long non-coding RNA (lncRNA) in TNM I stage (stage I) LUAD might lay the foundation for illumination of pathogenesis of LUAD and identification of potential therapeutic targets and novel diagnosis biomarkers for LUAD patients.
Association of miR-21 with esophageal cancer prognosis: a meta-analysis.
TLDR
The results support a prognostic role for miR-21 in EC and the association of elevated versus decreased miRNA-21 expression with EC prognosis was 1.87 [95% confidence interval (CI)): 1.37-2.55, P < 0.001].
Effects of acetylcholine on sling and clasp fibers of the human lower esophageal sphincter
TLDR
The aim of this study was to compare the functional properties of human LES clasp and sling muscles, and to look at their relationship with the expression of muscarinic receptors and intracellular Ca2+ concentration.
...
1
2
3
...