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Clazosentan (AXV-034343), a selective endothelin A receptor antagonist, in the prevention of cerebral vasospasm following severe aneurysmal subarachnoid hemorrhage: results of a randomized,
OBJECTIVE The goal of this study was to investigate the safety and tolerability of the novel endothelin A (ETA) receptor antagonist clazosentan in patients with subarachnoid hemorrhage (SAH) and itsExpand
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Spinal cord infarction: MR imaging and clinical features in 16 cases
Abstract. Spinal cord infarctions are rare and due to heterogeneous etiologies. The aim of the study was to analyze the MR imaging findings and evaluate their correlations with clinical symptoms inExpand
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Intraoperative Motor Evoked Potential Alteration in Intracranial Tumor Surgery and Its Relation to Signal Alteration in Postoperative Magnetic Resonance Imaging
OBJECTIVETo determine the degree to which the pattern of intraoperative isolated, unilateral alteration of motor evoked potential (MEP) in intracranial surgery was related to motor outcome andExpand
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Time Course in the Development of Cerebral Vasospasm after Experimental Subarachnoid Hemorrhage: Clinical and Neuroradiological Assessment of the Rat Double Hemorrhage Model
OBJECTIVE:The “double hemorrhage” model in the rat is frequently used to simulate delayed cerebral vasospasm (CVS) after subarachnoid hemorrhage (SAH) in humans. However, an exact neurological andExpand
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Focal laminar cortical infarcts following aneurysmal subarachnoid haemorrhage
Introduction The aim of this prospective study was to analyse small band-like cortical infarcts after subarachnoid haemorrhage (SAH) using magnetic resonance imaging (MRI) with reference toExpand
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Neuroradiological Viewpoint on the Diagnostics of Space-Occupying Brain Lesions
Conventional magnetic resonance (MR) imaging of space-occupying lesions may answer most of the questions concerning the diagnosis and subsequent treatment strategies if patient age, clinical andExpand
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Visual Search in Patients with Subcortical Vascular Dementia: Short Fixations but Long Reaction Times
Visual search is a cognitive function of high ecological relevance. It involves rapid alternations between allocating and shifting attention. In patients with Alzheimer’s disease, the duration ofExpand
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Perfusion-weighted MRI to evaluate cerebral autoregulation in aneurysmal subarachnoid haemorrhage
IntroductionThe aim of this study was to evaluate autoregulatory mechanisms in different vascular territories within the first week after aneurysmal subarachnoid haemorrhage (SAH) byExpand
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Effect of delayed cerebral vasospasm on cerebrovascular endothelin A receptor expression and function.
OBJECT The key role in the development of cerebral vasospasm after subarachnoid hemorrhage (SAH) is increasingly assigned to endothelin (ET)-1. Constriction of the cerebrovasculature by ET-1 isExpand
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Brain surface reformatted images for fast and easy localization of perirolandic lesions.
OBJECT The goal of this study was to evaluate a novel form of brain surface representation that allows simple, reliable mapping of the surface neuroanatomy for the preoperative evaluation of theExpand
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