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CHRM2 gene predisposes to alcohol dependence, drug dependence and affective disorders: results from an extended case-control structured association study.
- Xingguang Luo, H. Kranzler, L. Zuo, S. Wang, H. Blumberg, J. Gelernter
- Medicine, Biology
- Human molecular genetics
- 15 August 2005
Cholinergic muscarinic 2 receptor (CHRM2) is implicated in memory and cognition, functions impaired in many neuropsychiatric disorders. Wang et al. [Wang, J.C., Hinrichs, A.L., Stock, H., Budde, J.,… Expand
Down-regulated expression of SATB2 is associated with metastasis and poor prognosis in colorectal cancer.
To identify novel biomarkers of metastasis of colorectal cancer (CRC), we developed an orthotopic implantation model of murine CRC and selected in vivo M5, a subclone of the SW480 CRC cell line with… Expand
Genome‐wide DNA methylation profiles in hepatocellular carcinoma
Alterations in DNA methylation frequently occur in hepatocellular cancer (HCC). We have previously demonstrated that hypermethylation in candidate genes can be detected in plasma DNA before HCC… Expand
Diplotype trend regression analysis of the ADH gene cluster and the ALDH2 gene: multiple significant associations with alcohol dependence.
- Xingguang Luo, H. Kranzler, L. Zuo, S. Wang, N. Schork, J. Gelernter
- Biology, Medicine
- American journal of human genetics
- 1 June 2006
The set of alcohol-metabolizing enzymes has considerable genetic and functional complexity. The relationships between some alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) genes and… Expand
Epstein–Barr virus-encoded microRNA BART1 induces tumour metastasis by regulating PTEN-dependent pathways in nasopharyngeal carcinoma
Epstein–Barr virus (EBV), aetiologically linked to nasopharyngeal carcinoma (NPC), is the first human virus found to encode many miRNAs. However, how these viral miRNAs precisely regulate the tumour… Expand
Exploring genome-wide DNA methylation profiles altered in hepatocellular carcinoma using Infinium HumanMethylation 450 BeadChips
Hepatocellular carcinoma (HCC) incidence has increased in the US and also has one of the fastest growing death rates of any cancer. The purpose of the current study was to discover novel genome-wide… Expand
MiR-141 Suppresses the Migration and Invasion of HCC Cells by Targeting Tiam1
Background We have demonstrated that T lymphoma invasion and metastasis 1 (Tiam1) gene is associated with the poor prognosis of patients with hepatocellular carcinoma (HCC), and we used a… Expand
A Novel Coarse-to-Fine Scheme for Automatic Image Registration Based on SIFT and Mutual Information
- Maoguo Gong, S. Zhao, L. Jiao, Dayong Tian, S. Wang
- Mathematics, Computer Science
- IEEE Transactions on Geoscience and Remote…
- 1 July 2014
Automatic image registration is a vital yet challenging task, particularly for remote sensing images. A fully automatic registration approach which is accurate, robust, and fast is required. For this… Expand
Transcriptional patterns, biomarkers and pathways characterizing nasopharyngeal carcinoma of Southern China
BackgroundThe pathogenesis of nasopharyngeal carcinoma (NPC) is a complicated process involving genetic predisposition, Epstein-Bar Virus infection, and genetic alterations. Although some oncogenes… Expand
NK Cells Induce Apoptosis in Tubular Epithelial Cells and Contribute to Renal Ischemia-Reperfusion Injury1
Renal ischemia-reperfusion injury (IRI) can result in acute renal failure with mortality rates of 50% in severe cases. NK cells are important participants in early-stage innate immune responses.… Expand