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Sample size and optimal designs for reliability studies.
A method is developed to calculate the required number of subjects k in a reliability study, where reliability is measured using the intraclass correlation rho. The method is based on a functional… Expand
The results of direct and indirect treatment comparisons in meta-analysis of randomized controlled trials.
When little or no data directly comparing two treatments are available, investigators often rely on indirect comparisons from studies testing the treatments against a control or placebo. One approach… Expand
Estimating the error rates of diagnostic tests.
It is often required to evaluate the accuracy of a new diagnostic test against a standard test with unknown error rates. If the two tests are applied simultaneously to the same individuals from two… Expand
Higher vs lower positive end-expiratory pressure in patients with acute lung injury and acute respiratory distress syndrome: systematic review and meta-analysis.
CONTEXT Trials comparing higher vs lower levels of positive end-expiratory pressure (PEEP) in adults with acute lung injury or acute respiratory distress syndrome (ARDS) have been underpowered to… Expand
Incidence of and Risk Factors for Ventilator-Associated Pneumonia in Critically Ill Patients
A recent international prevalence study involving more than 1000 intensive care units indicated that pneumonia is responsible for almost half of the infections in critically ill patients in Europe… Expand
Caregiving process and caregiver burden: Conceptual models to guide research and practice
BackgroundParental care for a child with a developmental disability is an enormous responsibility, one that can far exceed that of typical parental care. While most parents adapt well to the… Expand
Properties of the summary receiver operating characteristic (SROC) curve for diagnostic test data.
- S. Walter
- Mathematics, Medicine
- Statistics in medicine
- 15 May 2002
The summary receiver operating characteristic (SROC) curve has been recommended to represent the performance of a diagnostic test, based on data from a meta-analysis. However, little is known about… Expand
High-frequency oscillation in early acute respiratory distress syndrome.
- N. Ferguson, D. Cook, +13 authors M. Meade
- The New England journal of medicine
- 27 February 2013
BACKGROUND Previous trials suggesting that high-frequency oscillatory ventilation (HFOV) reduced mortality among adults with the acute respiratory distress syndrome (ARDS) were limited by the use of… Expand
SARS among Critical Care Nurses, Toronto
To determine factors that predispose or protect healthcare workers from severe acute respiratory syndrome (SARS), we conducted a retrospective cohort study among 43 nurses who worked in two Toronto… Expand
A comparison of methods to detect publication bias in meta-analysis.
Meta-analyses are subject to bias for many of reasons, including publication bias. Asymmetry in a funnel plot of study size against treatment effect is often used to identify such bias. We compare… Expand