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Sample size and optimal designs for reliability studies.
TLDR
A functional approximation to earlier exact results is shown to have excellent agreement with the exact results and one can use it easily without intensive numerical computation.
Estimating the error rates of diagnostic tests.
TLDR
If the two tests are applied simultaneously to the same individuals from two populations with different disease prevalences, then the error rates of both tests and the true prevalences in both populations can be estimated by a maximum likelihood procedure.
Higher vs lower positive end-expiratory pressure in patients with acute lung injury and acute respiratory distress syndrome: systematic review and meta-analysis.
TLDR
Evaluating the association of higher vs lower PEEP with patient-important outcomes in adults with acute lung injury or ARDS who are receiving ventilation with low tidal volumes found that higher levels were associated with improved survival among the subgroup of patients with ARDS, but lower levels were not associated withImproved hospital survival.
Incidence of and Risk Factors for Ventilator-Associated Pneumonia in Critically Ill Patients
TLDR
This study examined factors associated with ventilator-associated pneumonia and explored baseline and time-dependent characteristics, including measures of illness severity, factors relating to mechanical ventilation, variables in the gastropulmonary route of infection, and drug exposure.
Caregiving process and caregiver burden: Conceptual models to guide research and practice
TLDR
Integration of these models used to describe the caregiving process from two diverse fields, pediatrics and geriatrics, into one comprehensive model suitable for this population of children with disabilities and their caregivers is proposed.
A comparison of methods to detect publication bias in meta‐analysis
TLDR
Based on the empirical type I error rates, a regression of treatment effect on sample size, weighted by the inverse of the variance of the logit of the pooled proportion (using the marginal total) is the preferred method.
High-frequency oscillation in early acute respiratory distress syndrome.
TLDR
In adults with moderate-to-severe ARDS, early application of HFOV, as compared with a ventilation strategy of low tidal volume and high positive end-expiratory pressure, does not reduce, and may increase, in-hospital mortality.
SARS among Critical Care Nurses, Toronto
TLDR
It is concluded that activities related to intubation increase SARS risk and use of a mask (particularly a N95 mask) is protective.
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