• Publications
  • Influence
Sample size and optimal designs for reliability studies.
A method is developed to calculate the required number of subjects k in a reliability study, where reliability is measured using the intraclass correlation rho. The method is based on a functionalExpand
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The results of direct and indirect treatment comparisons in meta-analysis of randomized controlled trials.
When little or no data directly comparing two treatments are available, investigators often rely on indirect comparisons from studies testing the treatments against a control or placebo. One approachExpand
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Estimating the error rates of diagnostic tests.
It is often required to evaluate the accuracy of a new diagnostic test against a standard test with unknown error rates. If the two tests are applied simultaneously to the same individuals from twoExpand
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Higher vs lower positive end-expiratory pressure in patients with acute lung injury and acute respiratory distress syndrome: systematic review and meta-analysis.
CONTEXT Trials comparing higher vs lower levels of positive end-expiratory pressure (PEEP) in adults with acute lung injury or acute respiratory distress syndrome (ARDS) have been underpowered toExpand
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Incidence of and Risk Factors for Ventilator-Associated Pneumonia in Critically Ill Patients
A recent international prevalence study involving more than 1000 intensive care units indicated that pneumonia is responsible for almost half of the infections in critically ill patients in EuropeExpand
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Caregiving process and caregiver burden: Conceptual models to guide research and practice
BackgroundParental care for a child with a developmental disability is an enormous responsibility, one that can far exceed that of typical parental care. While most parents adapt well to theExpand
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Properties of the summary receiver operating characteristic (SROC) curve for diagnostic test data.
  • S. Walter
  • Mathematics, Medicine
  • Statistics in medicine
  • 15 May 2002
The summary receiver operating characteristic (SROC) curve has been recommended to represent the performance of a diagnostic test, based on data from a meta-analysis. However, little is known aboutExpand
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High-frequency oscillation in early acute respiratory distress syndrome.
BACKGROUND Previous trials suggesting that high-frequency oscillatory ventilation (HFOV) reduced mortality among adults with the acute respiratory distress syndrome (ARDS) were limited by the use ofExpand
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SARS among Critical Care Nurses, Toronto
To determine factors that predispose or protect healthcare workers from severe acute respiratory syndrome (SARS), we conducted a retrospective cohort study among 43 nurses who worked in two TorontoExpand
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A comparison of methods to detect publication bias in meta-analysis.
Meta-analyses are subject to bias for many of reasons, including publication bias. Asymmetry in a funnel plot of study size against treatment effect is often used to identify such bias. We compareExpand
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