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Thyroid lymphoma: recent advances in diagnosis and optimal management strategies.
Primary thyroid lymphoma is rare, composing approximately 5% of all thyroid malignancies and less than 3% of all extranodal lymphomas. It typically presents as a rapidly enlarging goiter withExpand
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Molecular and therapeutic advances in the diagnosis and management of malignant pheochromocytomas and paragangliomas.
Pheochromocytomas (PCCs) and paragangliomas (PGLs) are rare catecholamine-secreting tumors derived from chromaffin cells originating in the neural crest. These tumors represent a significantExpand
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Biomarkers in Breast Cancer: Where Are We and Where Are We Going?
Biomarkers play an important role in the detection and management of patients with breast cancer. Thus, BRCA1/2 mutation testing is used for risk assessment in families with a high prevalence ofExpand
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Identifying palliative care issues in inpatients dying following stroke
BackgroundStroke leads to high mortality and morbidity but often there is a conflict between need for palliative care and avoidance of ‘therapeutic nihilism’.AimsWe aimed to elicit the palliativeExpand
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mTOR in breast cancer: differential expression in triple-negative and non-triple-negative tumors.
Triple-negative breast cancer (TNBC) is defined by the absence of estrogen receptors (ER), progesterone receptors (PR) and overexpression of HER2. Targeted therapy is currently unavailable for thisExpand
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Postmastectomy radiotherapy: indications and implications.
BACKGROUND Although breast conservation surgery, when combined with radiotherapy, has been shown to provide excellent locoregional control for breast cancer, approximately one third of women withExpand
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Does the modified Glasgow Prognostic Score (mGPS) have a prognostic role in esophageal cancer?
The modified Glasgow Prognostic Score (mGPS), which combines indices of decreased plasma albumin and elevated CRP, has reported independent prognostic significance in colorectal cancer, but its valueExpand
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Successful surgical management of early esophageal cancer in a patient with cystic fibrosis post-bilateral lung transplantation
We present the first reported case of successful surgical management of esophageal cancer post-lung transplantation for cystic fibrosis. This case of a 42-year-old man highlights the risk factors forExpand
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Benign breast papilloma: Is surgical excision necessary?
In many centers internationally, current standard of care is to excise all papillomas of the breast, despite recently reported low rates of upgrade to malignancy on final excision. The objective ofExpand
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The significance of receptor status discordance between breast cancer primary and brain metastasis
The cumulative incidence of brain metastases in breast cancer (BCBM) is 5%-10% and has increased in recent years. Metastasectomy rates for BCBM have accordingly increased with improvements inExpand
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