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Current Place of Monoamine Oxidase Inhibitors in the Treatment of Depression
This paper reviews the discovery and history of the use of irreversible monoamine oxidase (MAO) inhibitors (MAOIs) such as phenelzine, tranylcypromine and isocarboxazid, as well as the second
Reporting Guidelines for Clinical Pharmacokinetic Studies: The ClinPK Statement
TLDR
A tool to guide transparent and accurate reporting of clinical pharmacokinetic studies is developed using consensus methods to promote more consistent reporting of these studies and allow for better assessment of utility for clinical applications.
Evaluation of direct medical costs of hospitalization for febrile neutropenia
Treatment of febrile neutropenia (FN) is costly, because it typically involves hospitalization. As cancer rates continue to increase, the number of patients suffering from FN will also increase,
Milk thistle and indinavir: a randomized controlled pharmacokinetics study and meta-analysis
TLDR
Indinavir levels were not reduced significantly in the presence of milkThistle, and a meta-analysis of three milk thistle–indinavir trials revealed a non-significant pooled mean difference of 1% in AUC0-8.
Optimizing initial vancomycin dosing in burn patients.
The making of a user friendly MAOI diet.
TLDR
This work proposes an MAOI diet that has a solid scientific and clinical basis and that is, above all, practical and recommends that users avoid aged cheese; aged or cured meats; and tap beer.
Serum Concentrations of Salicylic Acid following Topically Applied Salicylate Derivatives
TLDR
A considerable amount of salicylic acid may be absorbed through the skin after topical application of methyl salicylate products and this may increase with multiple applications, so caution is warranted in patients for whom systemic saliylate may be hazardous or problematic.
Refining the MAOI diet: tyramine content of pizzas and soy products.
TLDR
Pizzas from large chain commercial outlets are safe for consumption with MAOIs, but caution must be exercised if ordering pizzas from smaller outlets or gourmet pizzas known to contain aged cheeses, and all soybean products should be avoided.
Cost-effectiveness of filgrastim and pegfilgrastim as primary prophylaxis against febrile neutropenia in lymphoma patients.
TLDR
Primary prophylaxis against febrile neutropenia with either filgrastim or pegfilgrastIM is not cost-effective in DLBCL patients.
Analysis of the hypericin and pseudohypericin content of commercially available St John's Wort preparations.
TLDR
A specific and sensitive liquid chromatographic method with fluorescent detection was used to specifically quantify the hypericin and pseudohypericin content in commercially purchased St John's wort products.
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