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- Publications
- Influence
Vesicle-Mediated Export and Assembly of Pore-Forming Oligomers of the Enterobacterial ClyA Cytotoxin
- S. Wai, Barbro Lindmark, +7 authors B. E. Uhlin
- Biology, Medicine
- Cell
- 3 October 2003
The ClyA protein is a pore-forming cytotoxin expressed by Escherichia coli and some other enterobacteria. It confers cytotoxic activity toward mammalian cells, but it has remained unknown how ClyA is… Expand
Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors
- Alistair B. Russell, Michele Leroux, +5 authors J. Mougous
- Biology, Medicine
- Nature
- 3 April 2013
Membranes allow the compartmentalization of biochemical processes and are therefore fundamental to life. The conservation of the cellular membrane, combined with its accessibility to secreted… Expand
A new Vibrio cholerae sRNA modulates colonization and affects release of outer membrane vesicles
- T. Song, Franziska Mika, +8 authors S. Wai
- Biology, Medicine
- Molecular microbiology
- 15 August 2008
We discovered a new small non‐coding RNA (sRNA) gene, vrrA of Vibrio cholerae O1 strain A1552. A vrrA mutant overproduces OmpA porin, and we demonstrate that the 140 nt VrrA RNA represses ompA… Expand
Vibrio cholerae O1 Strain TSI-4 Produces the Exopolysaccharide Materials That Determine Colony Morphology, Stress Resistance, and Biofilm Formation
- S. Wai, Y. Mizunoe, A. Takade, S. Kawabata, S. Yoshida
- Biology, Medicine
- Applied and Environmental Microbiology
- 1 October 1998
ABSTRACT Vibrio cholerae O1 strain TSI-4 (El Tor, Ogawa) can shift to a rugose colony morphology from its normal translucent colony morphology in response to nutrient starvation. We have investigated… Expand
Quorum Sensing Regulation of the Two hcp Alleles in Vibrio cholerae O1 Strains
- T. Ishikawa, P. Rompikuntal, Barbro Lindmark, D. Milton, S. Wai
- Biology, Medicine
- PloS one
- 24 August 2009
Background The type VI secretion system (T6SS) has emerged as a protein secretion system important to several Gram-negative bacterial species. One of the common components of the system is Hcp,… Expand
Horseshoe crab acetyl group-recognizing lectins involved in innate immunity are structurally related to fibrinogen.
- S. Gokudan, T. Muta, +7 authors S. Kawabata
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 31 August 1999
We have characterized and cloned newly isolated lectins from hemolymph plasma of the horseshoe crab Tachypleus tridentatus, which we named tachylectins 5A and 5B (TLs-5). TLs-5 agglutinated all types… Expand
The iron-binding protein Dps confers hydrogen peroxide stress resistance to Campylobacter jejuni.
- T. Ishikawa, Y. Mizunoe, +4 authors S. Yoshida
- Biology, Medicine
- Journal of bacteriology
- 1 February 2003
We identified and characterized the iron-binding protein Dps from Campylobacter jejuni. Electron microscopic analysis of this protein revealed a spherical structure of 8.5 nm in diameter, with an… Expand
Outer membrane vesicle-mediated release of cytolethal distending toxin (CDT) from Campylobacter jejuni
- Barbro Lindmark, P. Rompikuntal, +5 authors S. Wai
- Biology, Medicine
- BMC Microbiology
- 16 October 2009
BackgroundBackground: Cytolethal distending toxin (CDT) is one of the well-characterized virulence factors of Campylobacter jejuni, but it is unknown how CDT becomes surface-exposed or is released… Expand
A Vibrio cholerae protease needed for killing of Caenorhabditis elegans has a role in protection from natural predator grazing.
- K. Vaitkevicius, Barbro Lindmark, +8 authors S. Wai
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 13 June 2006
Vibrio cholerae is the causal bacterium of the diarrheal disease cholera, and its growth and survival are thought to be curtailed by bacteriovorous predators, e.g., ciliates and flagellates. We… Expand
Biochemical and functional characterization of Helicobacter pylori vesicles
- Annelie Olofsson, Anna Vallström, +8 authors A. Arnqvist
- Biology, Medicine
- Molecular microbiology
- 5 August 2010
Helicobacter pylori can cause peptic ulcer disease and/or gastric cancer. Adhesion of bacteria to the stomach mucosa is an important contributor to the vigour of infection and resulting virulence. H.… Expand