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HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system.
We report the discovery of the huntingtin interacting protein I (HIP-I) which binds specifically to the N-terminus of human huntingtin, both in the two-hybrid screen and in in vitro bindingExpand
SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates.
The mechanism by which aggregated polygins cause the selective neurodegeneration in Huntington's disease (HD) is unknown. Here, we show that the SH3GL3 protein, which is preferentially expressed inExpand
Identification of VCP/p97, Carboxyl Terminus of Hsp70-interacting Protein (CHIP), and Amphiphysin II Interaction Partners Using Membrane-based Human Proteome Arrays*S
Proteins mediate their biological function through interactions with other proteins. Therefore, the systematic identification and characterization of protein-protein interactions have become aExpand
using membrane-based human proteome arrays
Evidence for the Interaction of Endophilin A3 with Endogenous Kca2.3 Channels in PC12 Cells
Background/Aims: Small-conductance calcium-activated (SK) channels play an important role by controlling the after-hyperpolarization of excitable cells. The level of expression and density of theseExpand
PROTEIN CLASSIFICATION BY ANALYSIS OF CONFOCAL MICROSCOPIC IMAGES OF SINGLE CELLS
Proteins being present in a living cell fulfil a certain task in the cell. As a consequence of its functionality a protein is located in certain parts of the cell. If it is made visible the resultingExpand