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Hyaluronic acid modified chitosan nanoparticles for effective management of glaucoma: development, characterization, and evaluation
Haluronic acid modified chitosan nanoparticles loaded with TM and DH suggest that HA potentialy enhance the mucoadhesiveness and efficiency of CS-NPs and may be promising carrier for ocular drug delivery.
Nanocarriers in ocular drug delivery: an update review.
This review presents an overview of the various aspects of the ocular drug delivery, with special emphasis on nanocarrier based strategies, including structure of eye, its barriers, delivery routes and the challenges/limitations associated with development of novelnanocarriers.
Tamoxifen-loaded lecithin organogel (LO) for topical application: Development, optimization and characterization.
Systematically optimized biocompatible isotretinoin-loaded solid lipid nanoparticles (SLNs) for topical treatment of acne.
Nanocolloidal carriers of isotretinoin: antimicrobial activity against Propionibacterium acnes and dermatokinetic modeling.
Besides establishing ITR as an antimicrobial agent against acne-causing bacteria, the current work ratifies immense potential of nanocolloidal carriers like SLNs and NLCs to treat acne in a more efficient manner.
Impact of solid carriers and spray drying on pre/post-compression properties, dissolution rate and bioavailability of solid self-nanoemulsifying drug delivery system loaded with simvastatin
Novel phospholipid-based topical formulations of tamoxifen: evaluation for antipsoriatic activity using mouse-tail model
- A. Bhatia, Bhupinder Singh, S. Wadhwa, K. Raza, O. Katare
- BiologyPharmaceutical development and technology
- 1 March 2014
The results of these studies demonstrated immense potential of the topically applied TAM-encapsulated vesicular and micellar systems in psoriasis, thus calling for more comprehensive investigations to establish the role of TAM in the management of Psoriasis.
Chitosan and its role in ocular therapeutics.
- S. Wadhwa, R. Paliwal, S. Paliwal, S. Vyas
- BiologyMini reviews in medicinal chemistry
- 30 November 2009
This review discussed various aspects related to chitosan and chitOSan based formulations particularly developed for ocular therapeutics, resulting with its interaction to ocular tissues.
Phospholipid vesicles encapsulated bacteriophage: A novel approach to enhance phage biodistribution.
Coadministration of Polypeptide-k and Curcumin Through Solid Self-Nanoemulsifying Drug Delivery System for Better Therapeutic Effect Against Diabetes Mellitus: Formulation, Optimization,…
The results revealed better control of serum glucose level and other biochemical tests, such as liver parameters, lipid profiles, and antioxidant levels, as well as histological evaluation of pancreatic tissues in all the solid SNEDDS formulation as compared with their naive forms.