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Performance of Bayesian feedback to forecast lidocaine serum concentration: Evaluation of the prediction error and the prediction interval
The prediction performance of the Bayesian feedback method was evaluated with respect to accuracy and precision, and efficacy and safety (width of the prediction interval) on the basis of 90Expand
  • 9
  • 2
Predicting individual phenytoin dosage
In this paper, we compare the Bayesian method as applied to phenytoin to two other prediction methods (and a baseline, nonfeedback one). Expand
  • 46
  • 1
Evaluation of population (NONMEM) pharmacokinetic parameter estimates
The application of population pharmacokinetic analysis has received increasing attention in the last few years. The main goal of this report is to make investigators aware of the necessity ofExpand
  • 43
  • 1
Estimates of the population pharmacokinetic parameters and performance of Bayesian feedback: A sensitivity analysis
  • S. Vožeh, C. Steiner
  • Mathematics, Medicine
  • Journal of Pharmacokinetics and Biopharmaceutics
  • 1 October 1987
We investigated the influence of bias in the estimates of the population pharmacokinetic parameters on the performance of Bayesian feedback in achieving a desired drug serum concentration. ThreeExpand
  • 11
  • 1
Saliva lithium concentrations in the management of lithium therapy.
To define conditions under which saliva lithium carbonate concentrations can be used as a guide in lithium therapy, serum (Cp) and saliva (Cs) concentrations were determined simultaneously underExpand
  • 8
Computer-Assisted Lidocaine Dosage Using Adaptive Feedback Method
Abstract Lidocaine is a first line antiarrhythmic agent for treatment and prevention of severe acute ventricular arrhythmias in patients with myocardial infarction. Its efficacy and safety isExpand
  • 3
[Regulatory control of new medicines: help or hindrance?].
To answer the question of the benefit and the cost/benefit ratio of the activities of a drug regulatory agency, the most important, clinically relevant "products" of a licensing authority in general,Expand
[Contribution of computer technology to the improvement of drug therapy].
  • S. Vožeh
  • Medicine
  • Schweizerische Rundschau fur Medizin Praxis…
  • 22 April 1986
[Monitoring of therapy using drug concentration levels: Why? When? How?].
  • Samuel Vožeh
  • Medicine
  • Therapeutische Umschau. Revue therapeutique
  • 1 August 1990
Serum concentration measurements represent a tool that can help the physician to choose the optimal dose in an individual patient. Its application has been recommended for several drugs that show aExpand
[Drug level determination for optimization of drug therapy. Practical significance and new trends].
  • Samuel Vožeh
  • Medicine
  • Schweizerische Rundschau fur Medizin Praxis…
  • 4 December 1984