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Growth of White Matter in the Adolescent Brain: Role of Testosterone and Androgen Receptor
The growth of white matter during human adolescence shows a striking sexual dimorphism; the volume of white matter increases with age slightly in girls and steeply in boys. Here, we provide evidenceExpand
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Brain size and folding of the human cerebral cortex.
During evolution, the mammalian cerebral cortex has expanded disproportionately to brain volume. As a consequence, most mammals with large brains have profusely convoluted cortices. The human cortexExpand
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Estimating volumes of the pituitary gland from T1-weighted magnetic-resonance images: Effects of age, puberty, testosterone, and estradiol
TLDR
The pituitary gland is a key structure in the hypothalamic-pituitary-gonadal (HPG) axis--it plays an important role in sexual maturation during puberty. Expand
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Sex differences in the growth of white matter during adolescence
TLDR
We measured lobular volumes of white matter and white-matter "density" throughout the brain and estimated the myelination index using magnetisation-transfer ratio (MTR). Expand
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A Common Variant of the FTO Gene Is Associated With Not Only Increased Adiposity but Also Elevated Blood Pressure in French Canadians
Background—FTO is the first gene established as contributing to common forms of obesity. The gene is highly expressed in the hypothalamus and is thought to mediate this effect through its influenceExpand
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Maternal smoking during pregnancy is associated with epigenetic modifications of the brain‐derived neurotrophic factor‐6 exon in adolescent offspring
Prenatal exposure to maternal cigarette smoking (PEMCS) is associated with variations in brain and behavior in adolescence. Epigenetic mechanisms may mediate some of the consequences of PEMCS throughExpand
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Prenatal Exposure to Maternal Cigarette Smoking and the Adolescent Cerebral Cortex
Smoking during pregnancy is associated with long-term consequences on offspring behavior. We measured thickness of the cerebral cortex using magnetic resonance images obtained in 155 adolescentsExpand
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Genes, maternal smoking, and the offspring brain and body during adolescence: Design of the Saguenay Youth Study
The search for genes of complex traits is aided by the availability of multiple quantitative phenotypes collected in geographically isolated populations. Here we provide rationale for a large‐scaleExpand
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Brain volumes and Val66Met polymorphism of the BDNF gene: local or global effects?
A common Single-Nucleotide Polymorphism in the Brain-Derived Neurotrophic Factor (BDNF) gene coding the Val66Met substitution in the pro-BDNF protein has been associated with a number of behaviouralExpand
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Predictors of disrupted social participation in myotonic dystrophy type 1.
OBJECTIVE To identify personal and environmental predictors of the most disrupted participation domains in people with myotonic dystrophy type 1 (DM1). DESIGN Cross-sectional study. SETTINGExpand
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