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18F-FDG PET-CT in the evaluation of paraneoplastic syndromes: experience at a regional oncology centre
TLDR
PET-CT is a highly sensitive and specific imaging technique in the evaluation of PNS and adds confidence to clinical likelihood and is estimated to have 100% sensitivity, 82% specificity, 42% positive predictive value and 100% negative predictive value.
Rapid-acquisition myocardial perfusion scintigraphy (MPS) on a novel gamma camera using multipinhole collimation and miniaturized cadmium-zinc-telluride (CZT) detectors: prognostic value and
TLDR
MPS performed on a CZT solid-state detector camera with multipinhole collimation is an evolutionary development that provides reliable prognostic and diagnostic information, while significantly reducing image acquisition time.
Risk of malignancy in pulmonary nodules: A validation study of four prediction models.
TLDR
The Mayo and Brock models showed good accuracy for determining likelihood of malignancy in nodules detected on CT scan and in patients undergoing FDG PET-CT for nodule evaluation, the highest accuracy was seen for the model described by Herder et al.
FDG PET/CT in infection and inflammation--current and emerging clinical applications.
TLDR
The current and emerging evidence for the use of FDG PET/CT in a broad spectrum of disorders, such as fever of unknown origin, sarcoidosis, large vessel vasculitis, musculoskeletal infections, joint prosthesis or implant-related complications, human immunodeficiency virus (HIV)-related infections, and miscellaneous indications, including IgG4-related systemic disease are discussed.
Post-treatment FDG PET-CT in head and neck carcinoma: comparative analysis of 4 qualitative interpretative criteria in a large patient cohort
TLDR
All four IC have similar diagnostic performance characteristics although Porceddu and Deauville scores offered the best trade off of minimising indeterminate outcomes whilst maintaining a high NPV.
Efficacy of qualitative response assessment interpretation criteria at 18F-FDG PET-CT for predicting outcome in locally advanced cervical carcinoma treated with chemoradiotherapy
TLDR
Use of a 5-point qualitative scoring system to assess metabolic response to CRT in locally advanced cervical carcinoma predicts survival outcome and this prognostic information may help guide further patient management.
Functional Imaging Biomarkers: Potential to Guide an Individualised Approach to Radiotherapy.
TLDR
Considerable challenges remain before the implementation of functional imaging biomarkers into routine clinical practice, including the inherent temporal variability of biological processes within tumours, reproducibility of imaging, determination of optimal imaging technique/combinations, timing during treatment and design of appropriate validation studies.
Second-look PET-CT following an initial incomplete PET-CT response to (chemo)radiotherapy for head and neck squamous cell carcinoma
TLDR
PET-CT is a useful tool for response assessment following (chemo)radiotherapy for head and neck squamous cell carcinoma and can be used to spare patients unnecessary surgical intervention, suggesting the potential to avoid surgical intervention.
Comparative effectiveness of 18F-FDG PET-CT and contrast-enhanced CT in the diagnosis of suspected large-vessel vasculitis.
TLDR
FDG PET-CT demonstrated excellent accuracy whilst CECT mural thickening showed good accuracy in the diagnosis of LVV, suggesting CECT is a viable alternative for the assessment of LVV.
Occult nodal disease in patients with non-small-cell lung cancer who are suitable for stereotactic ablative body radiation.
TLDR
It is shown that approximately 1 in 11 patients with peripheral stage I NSCLC will have occult mediastinal/hilar nodal involvement at surgical resection, which suggests routine use of EBUS-TBNA for nodal staging in patients undergoing SABR might identify a greater proportion of patients with nodal disease.
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