S. V. van Eeden

Publications105
h-index41
Citations6,683
Highly Influential Citations212
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Cytokines involved in the systemic inflammatory response induced by exposure to particulate matter air pollutants (PM(10)).
Elevated levels of ambient particulate matter (PM(10)) have been associated with increased cardiopulmonary morbidity and mortality. We previously showed that the deposition of particles in the lung… Expand
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Particulate air pollution induces progression of atherosclerosis.
OBJECTIVES We sought to determine the effect of exposure to air pollution particulate matter <10 microm (PM(10)) on the progression of atherosclerosis in rabbits. BACKGROUND Epidemiologic studies… Expand
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Particulate matter induces cytokine expression in human bronchial epithelial cells.
The present study was designed to determine cytokines produced by primary human bronchial epithelial cells (HBECs) exposed to ambient air pollution particles (EHC-93). Cytokine messenger RNA (mRNA)… Expand
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The human bone marrow response to acute air pollution caused by forest fires.
Atmospheric pollution increases cardiopulmonary morbidity and mortality by unexplained mechanisms. Phagocytosis of fine particles (PM(10)) by rabbit alveolar macrophages elevates white blood cells… Expand
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Wood smoke exposure induces a pulmonary and systemic inflammatory response in firefighters
Epidemiological studies report an association between exposure to biomass smoke and cardiopulmonary morbidity. The mechanisms for this association are unclear. The aim of the present study was to… Expand
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Particulate matter air pollution exposure: role in the development and exacerbation of chronic obstructive pulmonary disease
Due to the rapid urbanization of the world population, a better understanding of the detrimental effects of exposure to urban air pollution on chronic lung disease is necessary. Strong… Expand
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Interleukin-6 changes deformability of neutrophils and induces their sequestration in the lung.
Interleukin-6 (IL-6) is an important mediator of both the hepatic and the bone marrow components of the acute-phase response. Previous studies from our laboratory have shown that cells released into… Expand
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Particulate matter air pollution exposure promotes recruitment of monocytes into atherosclerotic plaques.
Epidemiologic studies have shown an association between exposure to ambient particulate air pollution <10 microm in diameter (PM(10)) and increased cardiovascular morbidity and mortality. We… Expand
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Glucocorticoid-induced granulocytosis: contribution of marrow release and demargination of intravascular granulocytes.
BACKGROUND Glucocorticoid-induced granulocytosis has been attributed to enhanced release of polymorphonuclear leukocytes (PMNs) from bone marrow, delayed apoptosis, and reduced egress of PMNs into… Expand
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The response of human bone marrow to chronic cigarette smoking.
Chronic cigarette smoking in humans causes leukocytosis. Animal studies show that chronic smoking shortens the transit time of polymorphonuclear leukocytes (PMNLs) through the bone marrow. The… Expand
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