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DNA repair and antigenic variation in Trypanosoma brucei
t Inn kinetoplasti d flagellates such as Trypanosoma brucei, a smal percentag e of the thymine residuess in the nuclear DNA is replaced by the modified base (3-D-glucosyl-hydroxymethyluraci l (J),,Expand
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Parasite antigen-specific interleukin-10 and antibody reponses predict accelerated parasite clearance in Plasmodium falciparum malaria.
Using strict inclusion criteria, we conducted a hospital-based, case-control study in which 100 Gabonese children with severe Plasmodium falciparum malaria were matched for age, gender and provenanceExpand
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Antibody responses to Plasmodium falciparum: evolution according to the severity of a prior clinical episode and association with subsequent reinfection.
We measured sporozoite- and total parasite antigen-specific IgG and IgM antibodies before and after treatment in matched groups of Gabonese children who presented with either mild or severeExpand
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Expressionn site activation in Trypanosoma brucei with threee marked variant surface glycoprotein gene expressionn sites
t Thee genes for the Variant Surface Glycoprotei n (VSG) of Trypanosoma brucei are transcribed in telomericc expression sites (ESs). There are about 20 different ESs per trypanosome nucleus.Expand
DNAA modification and base excision repair in Trypanosoma brucei
t Basee excision repai r (BER) is an evolutionaril y conserved system which removes altered bases fromfrom DNA. The initial step in BER is carried out by DNA glycosylases which recognize alteredExpand