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Cooperative effects of isoflavones and exercise on bone and lipid metabolism in postmenopausal Japanese women: a randomized placebo-controlled trial.
The findings of this study suggest that the preventive effects of isoflavones on bone loss depend on the individual's intestinal flora for equol production. Expand
Effects of Isoflavone and Exercise on BMD and Fat Mass in Postmenopausal Japanese Women: A 1‐Year Randomized Placebo‐Controlled Trial
The combined intervention of isoflavone intake and walking exercise over 1 year in postmenopausal Japanese women exhibited a trend for a greater effect on prevention of bone loss at the total hip and… Expand
Effects of natural S‐equol supplements on overweight or obesity and metabolic syndrome in the Japanese, based on sex and equol status
The effects of a natural S‐equol supplement on metabolic parameters associated with overweight or obesity and metabolic syndrome are studied. Expand
Daidzein-metabolising phenotypes in relation to serum lipids and uric acid in adults in Guangzhou, China
Equol phenotypes might influence cardiovascular risk in Chinese adults aged 20–69 years and there were no significant differences in serum lipids, glucose and uric acid between O-DMA producers and non-producers. Expand
Effects of S-equol and natural S-equol supplement (SE5-OH) on the growth of MCF-7 in vitro and as tumors implanted into ovariectomized athymic mice.
- A. Onoda, Tomomi Ueno, S. Uchiyama, S. Hayashi, Kiyoko Kato, N. Wake
- Chemistry, Medicine
- Food and chemical toxicology : an international…
- 1 September 2011
Results suggest that S-Equol and natural S-equol in the supplement (SE5-OH), do not promote the progression of breast cancer. Expand
Identification of a Novel Dihydrodaidzein Racemase Essential for Biosynthesis of Equol from Daidzein in Lactococcus sp. Strain 20-92
- Y. Shimada, Masayuki Takahashi, Norihiro Miyazawa, Y. Abiru, S. Uchiyama, H. Hishigaki
- Biology, Medicine
- Applied and Environmental Microbiology
- 11 May 2012
This study identified a novel dihydrodaidzein racemase (l-DDRC) that is involved in equol biosynthesis in a lactic acid bacterium, Lactococcus sp. Expand
Identification of Two Novel Reductases Involved in Equol Biosynthesis in Lactococcus Strain 20–92
- Y. Shimada, Masayuki Takahashi, +4 authors H. Hishigaki
- Medicine, Chemistry
- Journal of Molecular Microbiology and…
- 1 January 2012
It is revealed that the transcription of the gene encoding daidzein reductase in Lactococcus strain 20–92 (L-DZNR), which is responsible for the first stage of the biosynthesis of equol from daidZEin, is regulated by the presence of daidzesin. Expand
A natural S-equol supplement alleviates hot flushes and other menopausal symptoms in equol nonproducing postmenopausal Japanese women.
This is the first trial to show beneficial effects of a 10-mg natural S-(-)equol supplement consumed daily for 12 weeks on major menopausal symptoms, specifically, hot flushes and neck or shoulder muscle stiffness, in postmenopausal Japanese women. Expand
Dietary and Lifestyle Correlates of Urinary Excretion Status of Equol in Japanese Women
Dairy product intake was significantly lower in women who excreted detectable equol levels in urine than in those who did not, suggesting that dairy product intake may be associated with the production of equol. Expand
A pilot study on the effects of S-equol compared to soy isoflavones on menopausal hot flash frequency.
S-equol, 10 mg/day, appears to be as effective as soy isoflavones at reducing hot flash frequency and more effective for relieving muscle and joint pain in postmenopausal women. Expand