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Calcium/phospholipid-dependent kinase recognizes sites in microtubule-associated protein 2 which are phosphorylated in living brain and are not accessible to other kinases.
Microtubule-associated protein 2 (MAP-2) purified after microtubule assembly cycles from bovine brain had been shown to contain about 10 esterified phosphates (mol/mol), which were relativelyExpand
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Effects of GTP on bound nitric oxide of soluble guanylate cyclase probed by resonance Raman spectroscopy.
Soluble guanylate cyclase (sGC) was isolated from bovine lung, and its resonance Raman (RR) spectra were investigated for the reduced, CO-bound (CO-sGC), NO-bound (NO-sGC), oxidized, and oxidizedExpand
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Expression of a Chemorepellent Factor, Slit2, in Peripheral Nerve Regeneration
The expression of mRNA for chemorepellent factors slit1 and slit2 in rat peripheral nerve regeneration was examined. The mRNA of slit2 increased when the continuity of basal lamina tubes wasExpand
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Visualization of gaseous monoxide reception by soluble guanylate cyclase in the rat retina
Immunohistochemistry using novel monoclonal antibodies (mAbs) allowed us to uncover tissue activities of soluble guanylate cyclase (sGC) fine tuned by NO and CO. Upon NO and CO applications in vitro,Expand
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Urinary metabolic fingerprinting for amiodarone-induced phospholipidosis in rats using FT-ICR MS.
In the research and development for new therapeutic compounds, there has been a focus on detecting the changes of metabolites induced by drug administration and finding surrogate markers to assessExpand
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Purification of bovine soluble guanylate cyclase and ADP-ribosylation on its small subunit by bacterial toxins.
Soluble guanylate cyclase (sGC) consisting of two different subunits (alpha: Mr = 74,000, beta: Mr = 69,000) was purified more than 12,000-fold in terms of specific activity from the supernatant ofExpand
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ADP-ribosylation of nonmuscle actin with component I of C2 toxin.
C2 toxin elaborated by Clostridium botulinum type C is composed of two dissimilar protein components, designated components I and II. Component I of the toxin caused ADP-ribosylation of a protein ofExpand
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Oscillation of ADP‐ribosyl cyclase activity during the cell cycle and function of cyclic ADP‐ribose in a unicellular organism, Euglena gracilis
In Euglena gracilis, the activity of ADP‐ribosyl cyclase, which produces cyclic ADP‐ribose, oscillated during the cell cycle in a synchronous culture induced by a light‐dark cycle, and a markedExpand
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Resonance Raman evidence for the presence of two heme pocket conformations with varied activities in CO-bound bovine soluble guanylate cyclase and their conversion.
Resonance Raman (RR) spectra of soluble guanylate cyclase (sGC) reported by five independent research groups have been classified as two types: sGC(1) and sGC(2). Here we demonstrate that the RRExpand
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EphB2 and ephrin-B1 expressed in the adult kidney regulate the cytoarchitecture of medullary tubule cells through Rho family GTPases
Eph receptors and ephrin ligands are membrane-bound cell-cell communication molecules with well-defined functions in development, but their expression patterns and functions in many adult tissues areExpand
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