Degradation of methyl and ethyl mercury into inorganic mercury by various phagocytic cells
- I. Suda, S. Totoki, T. Uchida, H. Takahashi
- BiologyArchives of Toxicology
- 2006
Examination of the ability of phagocytic cells to degrade MeHg or EtHg into inorganic mercury in vitro by collecting them from blood or peritoneal cavity of several species of animal suggested that the degradation of alkyl Hg by these cells might be an intraphagosomal event.
Degradation of methyl and ethyl mercury into inorganic mercury by oxygen free radical-producing systems: Involvement of hydroxyl radical
- I. Suda, S. Totoki, H. Takahashi
- ChemistryArchives of Toxicology
- 2005
Results suggested that •OH, but not $$O_{2^ - } $$ and H2O2, might be the oxygen free radical mainly responsible for the degradation of MeHg and EtHg.
Inhibition by equine alpha 2-macroglobulin of an N-succinyl-L-trialanine p-nitroanilide-hydrolyzing protease purified from pronase.
- H. Ueki, A. Motoshima, Y. Kubota
- BiologyChemical and pharmaceutical bulletin
- 25 October 1986
The results suggest that STA-protease binds to α2M both covalently and noncovalently, as does trypsin, and its hydrolytic activities towards casein and low-molecular-weight substrates are inhibited to various extents.