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Nonalcoholic fatty liver disease: a feature of the metabolic syndrome.
It is concluded that NAFLD, in the presence of normoglycemia and normal or moderately increased body weight, is characterized by clinical and laboratory data similar to those found in diabetes and obesity. Expand
A Multidimensional Index and Staging System for Idiopathic Pulmonary Fibrosis
The GAP models use commonly measured clinical and physiologic variables to predict mortality in patients with IPF and perform similarly in pooled follow-up visits. Expand
Safety and Diagnostic Yield of Transbronchial Lung Cryobiopsy in Diffuse Parenchymal Lung Diseases: A Comparative Study versus Video-Assisted Thoracoscopic Lung Biopsy and a Systematic Review of the…
Cryobiopsy is safe and has lower complication and mortality rates compared to SLB, and TBLC might be considered the first diagnostic approach for obtaining tissue in ILDs, reserving the surgical approach for cases in which TBLC is not diagnostic. Expand
The impact of lung cancer on survival of idiopathic pulmonary fibrosis.
In patients with IPF, LC has a significant adverse impact on survival, and diagnosis and treatment of LC in IPF are burdened by an increased incidence of severe complicating events, apparently as lethal as the cancer itself. Expand
Transbronchial Lung Cryobiopsy in the Diagnosis of Fibrotic Interstitial Lung Diseases
TBLC has a good diagnostic yield in the clinical-radiologic setting of f-DPLD without diagnostic HRCT features of usual interstitial pneumonia, and should be considered as a potential alternative to SLBx in f- DPLD. Expand
Bronchoscopic Lung Cryobiopsy Increases Diagnostic Confidence in the Multidisciplinary Diagnosis of Idiopathic Pulmonary Fibrosis.
- S. Tomassetti, A. Wells, +14 authors V. Poletti
- American journal of respiratory and critical care…
- 1 April 2016
BLC is a new biopsy method that has a meaningful impact on diagnostic confidence in the multidisciplinary diagnosis of interstitial lung disease and may prove useful in the diagnosis of IPF. Expand
Metformin in non-alcoholic steatohepatitis
Patients who had steatohepatitis but were not alcoholics were treated with metformin (500 mg three times a day for 4 months), an agent that improves hepatic insulin sensitivity and insulin sensitivity, and liver volume decreased. Expand
High resolution CT and histological findings in idiopathic pleuroparenchymal fibroelastosis: Features and differential diagnosis
Two further cases of IPPFE are described, reviewing CT, clinical and histological features, with no therapeutic options other than lung transplantation currently available, yet. Expand
Prolonged low-dose methylprednisolone in patients with severe COVID-19 pneumonia
In patients with severe COVID-19 pneumonia, early administration of prolonged MP treatment was associated with a significantly lower hazard of death (71%) and decreased ventilator dependence and Randomized controlled studies are needed to confirm these findings. Expand
Transbronchial biopsy is useful in predicting UIP pattern
Although sensitivity is low, the data suggest that even modest amount of patchy interstitial fibrosis, fibroblast foci, honeycomb changes detected on TBB can be highly predictive of a UIP pattern. Expand