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Daily home fortification with iron as ferrous fumarate versus NaFeEDTA: a randomised, placebo-controlled, non-inferiority trial in Kenyan children
TLDR
There was no evidence, either in per protocol analysis or intention-to-treat analysis, that home fortification with either of the iron interventions improved haemoglobin concentration, plasma ferritin concentration, Plasma transferrin receptor concentration or erythrocyte zinc protoporphyrin-haem ratio. Expand
Calcium homeostasis and low-frequency magnetic and electric field exposure: A systematic review and meta-analysis of in vitro studies.
TLDR
The results demonstrate that LF MF might influence the calcium homeostasis in cells in vitro, but the risk of bias and high heterogeneity weakens the analyses, and any potential clinical implications await further investigation. Expand
Late diagnosis of HIV infection in asymptomatic patients.
TLDR
There was no evidence that the CD4+ count at diagnosis progressively increased over time, nor that the proportion of VLP and LP decreased, and in a multivariate model older age, heterosexual transmission and intravenous drug use remained as independent factors associated with LP. Expand
Opportunities and challenges associated with the evaluation of chimeric antigen receptor T cells in real-life.
TLDR
The positive qualified opinion of the EBMT registry by EMA to monitor long-term efficacy and safety of commercial CAR-T cells created opportunities and challenges and was serving as linking-pin to launch a novelCAR-T cell community. Expand
Immune monitoring in allogeneic hematopoietic stem cell transplant recipients: a survey from the EBMT-CTIWP
TLDR
The post-transplant immune restoration is one of the main factors influencing the clinical outcome of allo-HSCT and a large number of clinical studies have been devoted to identify biomarkers predictive of a fast and robust immune reconstitution and of a favorable outcome. Expand
Comparison of home fortification with two iron formulations among Kenyan children: Rationale and design of a placebo-controlled non-inferiority trial
TLDR
If daily home fortification with a low dose of iron (3 mg NaFeEDTA) has similar or superior efficacy to a high dose (12.5 mg ferrous fumarate) then it would be the preferred choice for treatment of iron deficiency anaemia in children. Expand
HIV & Hepatitis in the Americas 28–30 April 2016, Mexico City, Mexico
TLDR
It is clear that innate and possibly adaptive immune function are still necessary for viral clearance even with highly effective DAA‐based regimens, and thus, it is possible that particularly as therapy is pushed to shorter and simpler combinations, HIV may again emerge as an issue necessitating special consideration. Expand
How to Monitor Immune Reconstitution Following Allogeneic Hematopoietic Stem Cell Transplantation: A Survey from the EBMT- Cellular Therapy & Immunobiology Working Party
TLDR
The results of this survey indicate that country- and center expertise are associated with heterogeneous and distinct protocols, and underline the clinical need to harmonize methods and to provide practical recommendations for monitoring post-transplant immune reconstitution, both for routine purposes and investigational studies. Expand